[PDF][PDF] The role of inflammatory gene polymorphisms in severe COVID-19: a review

JQ Yip, A Oo, YL Ng, KL Chin, KK Tan, JJH Chu… - Virology Journal, 2024 - Springer
The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has profoundly
impacted global healthcare systems and spurred extensive research efforts over the past …

Association between polymorphisms in TLR3, TICAM1 and IFNA1 genes and covid-19 severity in Southern Brazil

M Braga, MAS Shiga, PES Silva… - Expert Review of …, 2024 - Taylor & Francis
Background A distinct phenotype in Coronavirus disease 2019 (Covid-19) was observed in
severe patients, consisting of a highly impaired interferon (IFN) type I response, an …

[HTML][HTML] Genetic, Clinical, Epidemiological, and Immunological Profiling of IgG Response Duration after SARS-CoV-2 Infection

F Póvoa da Costa, KML Sarges, R Silva… - International Journal of …, 2024 - mdpi.com
The IgG response against SARS-CoV-2 infection can persist for over six months (long
response; LR). However, among 30% of those infected, the duration can be as short as three …

[HTML][HTML] Interleukin-1 Beta rs16944 and rs1143634 and Interleukin-6 Receptor rs12083537 Single Nucleotide Polymorphisms as Potential Predictors of COVID-19 …

IA Ahmed, TG Kharboush, HS Al-Amodi, HFM Kamel… - Pathogens, 2024 - mdpi.com
Host genetic variation has been recognized as a key predictor of diverse clinical sequelae
among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients …

Association of the IFNG +874T/A Polymorphism with Symptomatic COVID-19 Susceptibility

KML Sarges, F Póvoa da Costa, EF Santos… - Viruses, 2024 - mdpi.com
Tumor necrosis factor (TNF) and interferon-gamma (IFNγ) are important inflammatory
mediators in the development of cytokine storm syndrome (CSS). Single nucleotide …

[HTML][HTML] Equal Maintenance of Anti-SARS-CoV-2 Antibody Levels Induced by Heterologous and Homologous Regimens of the BNT162b2, ChAdOx1, CoronaVac and …

TA do Nascimento, PY Nogami, CF de Oliveira… - Vaccines, 2024 - mdpi.com
Several technological approaches have been used to develop vaccines against COVID-19,
including those based on inactivated viruses, viral vectors, and mRNA. This study aimed to …

Interaction Between Genetic Susceptibility and COVID-19 Pathogenesis in Pediatric Multisystem Inflammatory Disorders: The Role of Immune Responses

LN Chen, ZX Shou, X Jin - Viral Immunology, 2024 - liebertpub.com
Numerous studies have highlighted the emergence of coronavirus disease (COVID-19)
symptoms reminiscent of Kawasaki disease in children, including fever, heightened …

Association of Interleukin-6 (rs1800795) and Interleukin-10 (rs1800896) Genetic Polymorphisms with the Outcome of COVID-19 Infection: A Single Center Study

M El-Bendary, M Naemattalah, H Elalfy… - Viral …, 2024 - liebertpub.com
The corona virus disease-2019 (COVID-19) pandemic has affected most of the world with
varying degrees of morbidity and mortality. The presence of genetic polymorphisms may be …