Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …

Neurons have more extended and complex shapes than other cells and consequently face a
greater challenge in distributing and maintaining mitochondria throughout their arbors …

Recent studies suggest that mitochondria can be transferred between cells to support the
survival of metabolically compromised cells. However, whether intercellular mitochondria …

The past decade has witnessed an upsurge in studies demonstrating mitochondrial transfer
as one of the emerging mechanisms through which mesenchymal stem cells (MSCs) can …

Although fibrosis is a common pathological feature of most end-stage organ diseases, its
pathogenesis remains unclear. There is growing evidence that mitochondrial dysfunction …

Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …

Mesenchymal stem cells (MSCs) are multipotent cells which can proliferate and replace
dead cells in the body. MSCs also secrete immunomodulatory molecules, creating a …

Recently, we showed that generation of tumours in syngeneic mice by cells devoid of
mitochondrial (mt) DNA (ρ0 cells) is linked to the acquisition of the host mtDNA. However …

Mitochondria are complex intracellular organelles traditionally identified as the
powerhouses of eukaryotic cells due to their central role in bioenergetic metabolism. In …

Mitochondrial dysfunction is considered one of the hallmarks of ischemia/reperfusion injury.
Mitochondria are plastic organelles that undergo continuous biogenesis, fusion, and fission …