Making sense of gut feelings in the traumatic brain injury pathogenesis

LFF Royes, F Gomez-Pinilla - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Traumatic brain injury (TBI) is a devastating condition which often initiates a sequel of
neurological disorders that can last throughout lifespan. From metabolic perspective, TBI …

Oxysterols and 4-hydroxy-2-nonenal contribute to atherosclerotic plaque destabilization

S Gargiulo, G Testa, P Gamba, E Staurenghi… - Free Radical Biology …, 2017 - Elsevier
A growing bulk of evidence suggests that cholesterol oxidation products, known as
oxysterols, and 4-hydroxy-2-nonenal (HNE), the major proatherogenic components of …

Impact of brief exercise on circulating monocyte gene and microRNA expression: implications for atherosclerotic vascular disease

S Radom-Aizik, FP Zaldivar Jr, F Haddad… - Brain, behavior, and …, 2014 - Elsevier
Physical activity can prevent and/or attenuate atherosclerosis, a disease clearly linked to
inflammation. Paradoxically, even brief exercise induces a stress response and increases …

Quantification of Lipid-Rich Core in Carotid Atherosclerosis Using Magnetic Resonance T2 Mapping: Relation to Clinical Presentation

JT Chai, L Biasiolli, L Li, M Alkhalil, F Galassi… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The aim of this study was to: 1) provide tissue validation of quantitative T2
mapping to measure plaque lipid content; and 2) investigate whether this technique could …

3, 4-Dihydroxytoluene, a metabolite of rutin, inhibits inflammatory responses in lipopolysaccharide-activated macrophages by reducing the activation of NF-κB …

KY Su, CY Yu, YP Chen, KF Hua, YLS Chen - BMC complementary and …, 2014 - Springer
Abstract Background Saussurea involucrata (Kar. et Kir.)(S. involucrate), is a rare traditional
Chinese medicinal herb. Rutin and hispidulin as well as their metabolites are flavonoids of …

Advanced glycated albumin impairs HDL anti-inflammatory activity and primes macrophages for inflammatory response that reduces reverse cholesterol transport

LS Okuda, G Castilho, DDFM Rocco… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Objective: We investigated the effect of advanced glycated albumin (AGE-albumin) on
macrophage sensitivity to inflammation elicited by S100B calgranulin and …

Up-regulation of PCSK6 by lipid oxidation products: A possible role in atherosclerosis

G Testa, E Staurenghi, S Giannelli, B Sottero… - Biochimie, 2021 - Elsevier
Atherosclerosis is a degenerative disease characterized by lesions that develop in the wall
of large-and medium-sized arteries due to the accumulation of low-density lipoproteins …

TNF-α augmented Porphyromonas gingivalis invasion in human gingival epithelial cells through Rab5 and ICAM-1

Y Kato, M Hagiwara, Y Ishihara, R Isoda, S Sugiura… - BMC microbiology, 2014 - Springer
Background Tumor necrosis factor alpha (TNF-α) plays a central role in the initiation and
maintenance of immune responses to periodontopathic bacteria. However, excess TNF-α …

The inflammatory process underlying atherosclerosis

MT Montero-Vega - Critical Reviews™ in Immunology, 2012 - dl.begellhouse.com
Atherosclerosis is considered an inflammatory disease that starts and evolves in response to
cholesterol accumulation in the arterial intima of the large and medium arteries. In recent …

Lipoprotein apheresis downregulates IL-1α, IL-6 and TNF-α mRNA expression in severe dyslipidaemia

C Stefanutti, F Mazza, D Pasqualetti… - Atherosclerosis …, 2017 - Elsevier
Background and aims Dyslipidaemias are associated with cardiovascular mortality and
morbidity, driven by unstable atherosclerotic plaques with inflammatory infiltrates. Levels of …