Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease
Q Yan, S Liu, Y Sun, C Chen, S Yang, M Lin… - Journal of Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …
Antioxidant therapy and antioxidant-related bionanomaterials in diabetic wound healing
W Zhang, L Chen, Y Xiong, AC Panayi… - … in bioengineering and …, 2021 - frontiersin.org
Ulcers are a lower-extremity complication of diabetes with high recurrence rates. Oxidative
stress has been identified as a key factor in impaired diabetic wound healing …
stress has been identified as a key factor in impaired diabetic wound healing …
Pharmacotherapy against oxidative stress in chronic kidney disease: Promising small molecule natural products targeting nrf2-ho-1 signaling
The global burden of chronic kidney disease (CKD) intertwined with cardiovascular disease
has become a major health problem. Oxidative stress (OS) plays an important role in the …
has become a major health problem. Oxidative stress (OS) plays an important role in the …
The crosstalk between Sirt1 and Keap1/Nrf2/ARE anti-oxidative pathway forms a positive feedback loop to inhibit FN and TGF-β1 expressions in rat glomerular …
K Huang, X Gao, W Wei - Experimental cell research, 2017 - Elsevier
Oxidative stress aroused by advanced glycation-end products (AGEs) is a culprit in the
pathological progression of diabetic nephropathy. Both Sirt1 and the Keap1/Nrf2/ARE anti …
pathological progression of diabetic nephropathy. Both Sirt1 and the Keap1/Nrf2/ARE anti …
A Review on the Antidiabetic Properties of Moringa oleifera Extracts: Focusing on Oxidative Stress and Inflammation as Main Therapeutic Targets
Moringa oleifera is one of the popular plants that have shown significant health benefits.
Certainly, preclinical evidence (predominantly from animal models) summarized in the …
Certainly, preclinical evidence (predominantly from animal models) summarized in the …
Molecular pharmacology of rosmarinic and salvianolic acids: Potential seeds for Alzheimer's and vascular dementia drugs
S Habtemariam - International Journal of Molecular Sciences, 2018 - mdpi.com
Both caffeic acid and 3, 4-dihydroxyphenyllactic acid (danshensu) are synthesized through
two distinct routs of the shikimic acid biosynthesis pathway. In many plants, especially the …
two distinct routs of the shikimic acid biosynthesis pathway. In many plants, especially the …
Salvianolic acid A protects against diabetic nephropathy through ameliorating glomerular endothelial dysfunction via inhibiting AGE-RAGE signaling
B Hou, G Qiang, Y Zhao, X Yang, X Chen… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: Glomerular endothelium dysfunction leads to the progression of
renal architectonic and functional abnormalities in early-stage diabetic nephropathy (DN) …
renal architectonic and functional abnormalities in early-stage diabetic nephropathy (DN) …
Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK‐3β/Nrf2 Signaling Pathway and Inhibiting the NF‐κB Signaling Pathway in …
H Zhang, J Wang, Y Wang, C Gao, Y Gu… - Oxidative Medicine …, 2019 - Wiley Online Library
Salvianolic acid A (SAA) is a bioactive polyphenol extracted from Salviae miltiorrhizae
Bunge, which possesses a variety of pharmacological activities. In our previous study, we …
Bunge, which possesses a variety of pharmacological activities. In our previous study, we …
Salvianolic acid A alleviates ischemic brain injury through the inhibition of inflammation and apoptosis and the promotion of neurogenesis in mice
MY Chien, CH Chuang, CM Chern, KT Liou… - Free Radical Biology …, 2016 - Elsevier
Salvianolic acid A (SalA), a chemical type of caffeic acid trimer, has drawn great attention for
its potent bioactivities against ischemia-induced injury both in vitro and in vivo. In this study …
its potent bioactivities against ischemia-induced injury both in vitro and in vivo. In this study …
[HTML][HTML] Pharmacodynamic substances in Salvia miltiorrhiza for prevention and treatment of hyperlipidemia and coronary heart disease based on lipidomics …
G Sun, X Li, J Wei, T Zhang, B Li, M Chen… - Biomedicine & …, 2021 - Elsevier
In this study, untargeted lipidomics based on UPLC-Q/TOF-MS, network pharmacology and
atomic force microscopy were used to explore the common biomarkers of hyperlipidemia …
atomic force microscopy were used to explore the common biomarkers of hyperlipidemia …