A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer
RM Robertson, J Yao, S Gajewski, G Kumar… - Nature structural & …, 2017 - nature.com
Phosphatidic acid (PA), the central intermediate in membrane phospholipid synthesis, is
generated by two acyltransferases in a pathway conserved in all life forms. The second step …
generated by two acyltransferases in a pathway conserved in all life forms. The second step …
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry
N Tavernier, Y Thomas, S Vigneron… - Nature …, 2021 - nature.com
Abstract Polo-like kinase 1 (Plk1) is instrumental for mitotic entry and progression. Plk1 is
activated by phosphorylation on a conserved residue Thr210 in its activation segment by the …
activated by phosphorylation on a conserved residue Thr210 in its activation segment by the …
The Aurora B-controlled PP1/RepoMan complex determines the spatial and temporal distribution of mitotic H2B S6 phosphorylation
M Pfisterer, R Robert, VV Saul, A Pritz… - Open …, 2024 - royalsocietypublishing.org
The precise spatial and temporal control of histone phosphorylations is important for the
ordered progression through the different phases of mitosis. The phosphorylation of H2B at …
ordered progression through the different phases of mitosis. The phosphorylation of H2B at …
Link of zygotic genome activation and cell cycle control
B Liu, J Grosshans - Zygotic Genome Activation: Methods and Protocols, 2017 - Springer
The activation of the zygotic genome and onset of transcription in blastula embryos is linked
to changes in cell behavior and remodeling of the cell cycle and constitutes a transition from …
to changes in cell behavior and remodeling of the cell cycle and constitutes a transition from …
Proximity mapping of human separase by the BioID approach
FG Agircan, S Hata, C Nussbaum-Krammer… - Biochemical and …, 2016 - Elsevier
Separase is a caspase-like cysteine protease that is best known for its essential role during
the metaphase-to-anaphase transition when it cleaves the cohesin ring complex that keeps …
the metaphase-to-anaphase transition when it cleaves the cohesin ring complex that keeps …
Induction of a Spindle-Assembly-Competent M phase in Xenopus egg extracts
JS Bisht, M Tomschik, JC Gatlin - Current Biology, 2019 - cell.com
Normal mitotic spindle assembly is a prerequisite for faithful chromosome segregation and
unperturbed cell-cycle progression. Precise functioning of the spindle machinery relies on …
unperturbed cell-cycle progression. Precise functioning of the spindle machinery relies on …
Investigating RSA-1-dependent PP2A functions in C. elegans mitotic spindle assembly
KI Lange - 2015 - era.library.ualberta.ca
Spindle assembly pathways are conserved in many organisms. Defects in spindle assembly
can result in aneuploidy, a common cause of cell death and cancer. A better understanding …
can result in aneuploidy, a common cause of cell death and cancer. A better understanding …