Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

Age-related T cell dysfunction can lead to failure of immune tolerance mechanisms, resulting
in aberrant T cell-driven cytokine and cytotoxic responses that ultimately cause tissue …

Background The diagnosis of acute myocarditis typically requires either endomyocardial
biopsy (which is invasive) or cardiovascular magnetic resonance imaging (which is not …

Sarcopenia, a geriatric syndrome that is characterized by a progressive and generalized
skeletal muscle disorder, can be associated with many comorbidities, including obesity …

Multiple Sclerosis (MS) is a major cause of neurological disability, which increases
predominantly during disease progression as a result of cortical and grey matter structures …

Calcific aortic valve disease (CAVD), and its clinical manifestation that is calcific aortic valve
stenosis, is the leading cause for valve disease within the developed world, with no current …

Acute coronary syndrome (ACS) is a major cause of acute death worldwide. Both innate and
adaptive immunity regulate atherosclerosis progression, plaque stability, and thrombus …

Chronic inflammatory rheumatoid diseases (CIRD) such as rheumatoid arthritis, systemic
lupus erythematosus, and systemic sclerosis are an important risk factor for the development …

Once regarded as an experimental artefact, cytotoxic CD4+ T cells (CD4 CTL) are presently
recognized as a biologically relevant T cell subset with important functions in anti-viral, anti …

Aims Long non-coding RNAs (lncRNAs) have been found to be involved in the
pathogenesis of coronary artery disease (CAD). However, it remains to be established …