[HTML][HTML] Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression

B Guo, M Zhang, W Hao, Y Wang, T Zhang… - Translational …, 2023 - nature.com
Mood disorders are associated with elevated inflammation, and the reduction of symptoms
after multiple treatments is often accompanied by pro-inflammation restoration. A variety of …

[HTML][HTML] Noradrenergic and cholinergic systems take centre stage in neuropsychiatric diseases of ageing

IF Orlando, JM Shine, TW Robbins, JB Rowe… - Neuroscience & …, 2023 - Elsevier
Noradrenergic and cholinergic systems are among the most vulnerable brain systems in
neuropsychiatric diseases of ageing, including Alzheimer's disease, Parkinson's disease …

Cholinergic nervous system and glaucoma: From basic science to clinical applications

MA Faiq, G Wollstein, JS Schuman, KC Chan - Progress in retinal and eye …, 2019 - Elsevier
The cholinergic system has a crucial role to play in visual function. Although cholinergic
drugs have been a focus of attention as glaucoma medications for reducing eye pressure …

New perspectives on the basal forebrain cholinergic system in Alzheimer's disease

AS Berry, TM Harrison - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
The basal forebrain cholinergic system (BFCS) has long been implicated in age-related
cognitive changes and the pathophysiology of Alzheimer's disease (AD). Limitations of …

Neurotoxicity of e-cigarettes

JA Ruszkiewicz, Z Zhang, FM Gonçalves… - Food and Chemical …, 2020 - Elsevier
It appears that electronic cigarettes (EC) are a less harmful alternative to conventional
cigarette (CC) smoking, as they generate substantially lower levels of harmful carcinogens …

[HTML][HTML] Autoimmunity to neuronal nicotinic acetylcholine receptors

M Pechlivanidou, E Ninou, K Karagiorgou… - Pharmacological …, 2023 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) are widely expressed in many and diverse cell
types, participating in various functions of cells, tissues and systems. In this review, we focus …

[HTML][HTML] Pathophysiology of nAChRs: limbic circuits and related disorders

YS Mineur, AR Soares, IM Etherington… - Pharmacological …, 2023 - Elsevier
Human epidemiological studies have identified links between nicotine intake and stress
disorders, including anxiety, depression and PTSD. Here we review the clinical evidence for …

[HTML][HTML] Mammalian susceptibility to a neonicotinoid insecticide after fetal and early postnatal exposure

AP Burke, Y Niibori, H Terayama, M Ito, C Pidgeon… - Scientific reports, 2018 - nature.com
Neonicotinoids have become the most widely used class of insecticides world-wide.
Although numerous studies have documented neonicotinoid toxicity in bees and other …

nAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives

V Parikh, MG Kutlu, TJ Gould - Schizophrenia research, 2016 - Elsevier
Introduction The prevalence of tobacco use in the population with schizophrenia is
enormously high. Moreover, nicotine dependence is found to be associated with symptom …

NOAEL-dose of a neonicotinoid pesticide, clothianidin, acutely induce anxiety-related behavior with human-audible vocalizations in male mice in a novel environment

T Hirano, S Yanai, T Takada, N Yoneda, T Omotehara… - Toxicology Letters, 2018 - Elsevier
Neonicotinoids are novel systemic pesticides acting as agonists on the nicotinic
acetylcholine receptors (nAChRs) of insects. Experimental studies have revealed that …