Psoriasis is a chronic inflammatory skin disorder, and current treatments include topical
therapies, phototherapy, systemic immune modulators, and biologics, aiming to alleviate …

Psoriasis is an immune cell-mediated inflammatory skin disease. The interleukin (IL) 23/IL17
axis plays an important role in the development of psoriasis. The effectiveness of biologic …

Psoriatic arthritis is an inflammatory arthropathy frequently associated with psoriasis and
several other comorbidities. The goal of this review is to summarize the available evidence …

Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are
increasing year by year. AIDs are produced by the immune system's misidentification of self …

Background Drug survival, defined as the length of time from initiation to discontinuation of a
given therapy, allows comparisons between drugs, helps to predict patient's likelihood of …

Introduction: Psoriasis is a chronic, immune-mediated disease with significant associated
comorbidities. Its pathogenesis is likely multifactorial, however, the interleukin-23/T helper …

Objective To investigate the efficacy and safety of brodalumab, a fully human anti-interleukin-
17 receptor A monoclonal antibody, in patients with axial spondyloarthritis (axSpA). Methods …

The complex crosstalk between the immune and the skeletal systems plays an
indispensable role in the maintenance of skeletal homeostasis. Various cytokines are …

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease affecting
areas with a high density of apocrine glands and characterized by subcutaneous nodules …

The stimulator of interferon genes (STING) is a critical protein in the activation of the immune
system in response to DNA. It can participate the inflammatory response process by …