Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages

S Xia, L Wang, Y Zhu, L Lu, S Jiang - Signal Transduction and Targeted …, 2022 - nature.com
Recently, a large number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) variants continuously emerged and posed a major threat to global public health. Among …

Ferritin–a multifaceted protein scaffold for biotherapeutics

NK Lee, S Cho, IS Kim - Experimental & Molecular Medicine, 2022 - nature.com
The ferritin nanocage is an endogenous protein that exists in almost all mammals. Its hollow
spherical structure that naturally stores iron ions has been diversely exploited by …

Protein-based nanocages for vaccine development

SA Kim, Y Lee, Y Ko, S Kim, GB Kim, NK Lee… - Journal of Controlled …, 2023 - Elsevier
Protein nanocages have attracted considerable attention in various fields of nanomedicine
due to their intrinsic properties, including biocompatibility, biodegradability, high structural …

Design of protein-binding peptides with controlled binding affinity: the case of SARS-CoV-2 receptor binding domain and angiotensin-converting enzyme 2 derived …

G Parisi, R Piacentini, A Incocciati… - Frontiers in Molecular …, 2024 - frontiersin.org
The development of methods able to modulate the binding affinity between proteins and
peptides is of paramount biotechnological interest in view of a vast range of applications that …

A Thermal-Stable Protein Nanoparticle That Stimulates Long Lasting Humoral Immune Response

TT Wong, GG Liou, MC Kan - Vaccines, 2023 - mdpi.com
A thermally stable vaccine platform is considered the missing piece of vaccine technology. In
this article, we reported the creation of a novel protein nanoparticle and assessed its ability …

Characterization of SARS-CoV-2 Convalescent Patients' Serological Repertoire Reveals High Prevalence of Iso-RBD Antibodies

NC Curtis, S Shin, AP Hederman, RI Connor… - bioRxiv, 2023 - biorxiv.org
While our understanding of SARS-CoV-2 pathogenesis and antibody responses following
infection and vaccination has improved tremendously since the outbreak in 2019, the …

A novel strategy for an anti-idiotype vaccine: nanobody mimicking neutralization epitope of porcine circovirus type 2

Y Deng, Y Sheng, G Zhang, Y Sun, L Wang… - Journal of …, 2024 - Am Soc Microbiol
Vaccination is the most effective method to protect humans and animals from diseases. Anti-
idiotype vaccines are safer due to their absence of pathogens. However, the commercial …

Implementation of the Admission Process of Patients Under the Public Crisis Situation of COVID-19 Pandemic: A Real-World Case Study

X Zhang, Z Yang, J Chen, C Zhang… - Journal of …, 2023 - Taylor & Francis
Purpose To clarify the implementation of the admission process under the public crisis of
COVID-19 pandemic. Methods A real-world study was conducted to collect data on the …

[HTML][HTML] Antigen Delivery Systems: Past, Present, and Future

HJ Ko, YJ Kim - Biomolecules & Therapeutics, 2023 - ncbi.nlm.nih.gov
The COVID-19 pandemic has increased demand for safe and effective vaccines. Research
to develop vaccines against diseases including Middle East respiratory syndrome …

Macromolecular interactions in solution-Interferometric and turbidimetric studies

R Piacentini - 2023 - iris.uniroma1.it
In the present doctoral thesis, the investigation of macromolecule interactions in three
different biochemical systems is reported. Exploiting the advantages of two novel and …