Overview and update on cytomegalovirus-associated anterior uveitis and glaucoma

Z Ye, Y Yang, W Ke, Y Li, K Wang… - Frontiers in Public Health, 2023 - frontiersin.org
Cytomegalovirus anterior uveitis is the most common ocular inflammatory disease caused
by cytomegalovirus infection. It mainly occurs in middle-aged males with competent …

Optimizing antiviral dosing for HSV and CMV treatment in immunocompromised patients

DW Huntjens, JA Dijkstra, LN Verwiel, M Slijkhuis… - Pharmaceutics, 2023 - mdpi.com
Herpes simplex virus (HSV) and cytomegalovirus (CMV) are DNA viruses that are common
among humans. Severely immunocompromised patients are at increased risk of developing …

Application of machine-learning models to predict the ganciclovir and valganciclovir exposure in children using a limited sampling strategy

L Ponthier, B Franck, J Autmizguine… - Antimicrobial Agents …, 2024 - journals.asm.org
Intravenous ganciclovir and oral valganciclovir display significant variability in ganciclovir
pharmacokinetics, particularly in children. Therapeutic drug monitoring currently relies on …

At-Home Foscarnet Administration in Patients with Cytomegalovirus Infection Post-Allogeneic Stem Cell Transplantation: A Unicentric, Safe, and Feasible Program

S Ruiz-Boy, A Pedraza, M Prat, MQ Salas, E Carcelero… - Pharmaceuticals, 2023 - mdpi.com
Cytomegalovirus (CMV) infection is a relevant cause of morbimortality in patients receiving
allogeneic stem cell transplantation (allo-HCT). Foscarnet (FCN) is an effective drug against …

Platinum-Nucleos (t) ide Compounds as Possible Antimetabolites for Antitumor/Antiviral Therapy: Properties and Perspectives

F De Castro, E Stefàno, E De Luca, M Benedetti… - Pharmaceutics, 2023 - mdpi.com
Nucleoside analogues (NAs) are a family of compounds which include a variety of purine
and pyrimidine derivatives, widely used as anticancer and antiviral agents. For their ability to …

Update on Epidemiology and Outcomes of Infection in Pediatric Organ Transplant Recipients

DE Dulek - Infectious Disease Clinics, 2023 - id.theclinics.com
Pediatric organ transplant recipients have many of the same infectious complications as
adults solid organ transplant (SOT) recipients. However, key differences exist in the …

Cytomegalovirus in haematopoietic cell transplantation-The troll is still there.

S Voigt - Best Practice & Research Clinical Haematology, 2024 - Elsevier
Patients undergoing allogeneic haematopoietic cell transplantation are prone to
complications caused by viral infections. Cytomegalovirus (CMV) considerably impacts …

[HTML][HTML] Efficacy of ganciclovir in the treatment of cytomegalovirus (CMV) infection in infants and its effect on inflammatory reaction and immune function

X Lin, Y Wan, Y Liu - American Journal of Translational Research, 2023 - ncbi.nlm.nih.gov
Objective: To investigate the efficacy of ganciclovir in the treatment of cytomegalovirus
(CMV) infection in infants and its effect on inflammatory reaction and immune function …

What's New: Updates on Cytomegalovirus in Solid Organ Transplantation

AG Stewart, CN Kotton - Transplantation, 2024 - journals.lww.com
Cytomegalovirus (CMV) is one of the most common infections occurring after solid organ
transplantation. This high burden of disease, which incurs sizeable morbidity, may be …

Rapid determination of acyclovir, its main metabolite 9‐carboxymethoxymethylguanine, ganciclovir, and penciclovir in human serum using LC–MS/MS

A Ärlemalm, A Helldén, L Karlsson… - Biomedical …, 2022 - Wiley Online Library
A novel MS‐based analytical method for simultaneous analysis of the antiviral drugs
acyclovir, its metabolite 9‐carboxymethoxymethylguanine, ganciclovir, and penciclovir in …