Prefrontal cortex development in health and disease: lessons from rodents and humans
M Chini, IL Hanganu-Opatz - Trends in neurosciences, 2021 - cell.com
The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …
Regeneration of spinal cord connectivity through stem cell transplantation and biomaterial scaffolds
H Katoh, K Yokota, MG Fehlings - Frontiers in cellular neuroscience, 2019 - frontiersin.org
Significant progress has been made in the treatment of spinal cord injury (SCI). Advances in
post-trauma management and intensive rehabilitation have significantly improved the …
post-trauma management and intensive rehabilitation have significantly improved the …
[HTML][HTML] Saturated reconstruction of a volume of neocortex
We describe automated technologies to probe the structure of neural tissue at nanometer
resolution and use them to generate a saturated reconstruction of a sub-volume of mouse …
resolution and use them to generate a saturated reconstruction of a sub-volume of mouse …
Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
F Mirabella, G Desiato, S Mancinelli, G Fossati… - Immunity, 2021 - cell.com
Early prenatal inflammatory conditions are thought to be a risk factor for different
neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy …
neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy …
[HTML][HTML] Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders
KP Lesch, J Waider - Neuron, 2012 - cell.com
Serotonin (5-HT) shapes brain networks during development and modulates a wide
spectrum of essential neuronal functions ranging from perception and cognitive appraisal to …
spectrum of essential neuronal functions ranging from perception and cognitive appraisal to …
The calcium channel subunit Alpha2delta2 suppresses axon regeneration in the adult CNS
A Tedeschi, S Dupraz, CJ Laskowski, J Xue, T Ulas… - Neuron, 2016 - cell.com
Injuries to the adult CNS often result in permanent disabilities because neurons lose the
ability to regenerate their axon during development. Here, whole transcriptome sequencing …
ability to regenerate their axon during development. Here, whole transcriptome sequencing …
Specification of synaptic connectivity by cell surface interactions
The molecular diversification of cell surface molecules has long been postulated to impart
specific surface identities on neuronal cell types. The existence of unique cell surface …
specific surface identities on neuronal cell types. The existence of unique cell surface …
The perineuronal net and the control of CNS plasticity
D Wang, J Fawcett - Cell and tissue research, 2012 - Springer
Perineuronal nets (PNNs) are reticular structures that surround the cell body of many
neurones, and extend along their dendrites. They are considered to be a specialized …
neurones, and extend along their dendrites. They are considered to be a specialized …
[HTML][HTML] FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development
Latrophilins (LPHNs) are a small family of G protein-coupled receptors known to mediate the
massive synaptic exocytosis caused by the black widow spider venom α-latrotoxin, but their …
massive synaptic exocytosis caused by the black widow spider venom α-latrotoxin, but their …