Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
Neuroblastoma origin and therapeutic targets for immunotherapy
IV Kholodenko, DV Kalinovsky… - Journal of …, 2018 - Wiley Online Library
Neuroblastoma is a pediatric solid cancer of heterogeneous clinical behavior. The unique
features of this type of cancer frequently hamper the process of determining clinical …
features of this type of cancer frequently hamper the process of determining clinical …
[HTML][HTML] Tumoral heterogeneity in neuroblastoma
RL Gomez, S Ibragimova, R Ramachandran… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Neuroblastoma is a solid, neuroendocrine tumor with divergent clinical behavior ranging
from asymptomatic to fatal. The diverse clinical presentations of neuroblastoma are directly …
from asymptomatic to fatal. The diverse clinical presentations of neuroblastoma are directly …
[HTML][HTML] Understanding cancer stem cells and plasticity: Towards better therapeutics
NM Warrier, N Kelkar, CT Johnson… - European Journal of …, 2023 - Elsevier
The ability of cancer cells to finally overcome various lines of treatment in due course has
always baffled the scientific community. Even with the most promising therapies, relapse is …
always baffled the scientific community. Even with the most promising therapies, relapse is …
Hypoxia predicts poor prognosis in neuroblastoma patients and associates with biological mechanisms involved in telomerase activation and tumor microenvironment …
D Cangelosi, M Morini, N Zanardi, AR Sementa… - Cancers, 2020 - mdpi.com
The biological and clinical heterogeneity of neuroblastoma (NB) demands novel biomarkers
and therapeutic targets in order to drive the most appropriate treatment for each patient …
and therapeutic targets in order to drive the most appropriate treatment for each patient …
[HTML][HTML] Preclinical models for neuroblastoma: Advances and challenges
Neuroblastoma is a paediatric cancer of the sympathetic nervous system and the most
common solid tumour of infancy, contributing to 15% of paediatric oncology deaths. Current …
common solid tumour of infancy, contributing to 15% of paediatric oncology deaths. Current …
HNF4A-AS1-encoded small peptide promotes self-renewal and aggressiveness of neuroblastoma stem cells via eEF1A1-repressed SMAD4 transactivation
H Song, J Wang, X Wang, B Yuan, D Li, A Hu, Y Guo… - Oncogene, 2022 - nature.com
Cancer stem cells play crucial roles in tumorigenesis and aggressiveness, while regulatory
mechanisms in neuroblastoma (NB), a pediatric extracranial malignancy with highest …
mechanisms in neuroblastoma (NB), a pediatric extracranial malignancy with highest …
[HTML][HTML] A physiologically relevant 3D collagen-based scaffold–neuroblastoma cell system exhibits chemosensitivity similar to orthotopic xenograft models
Abstract 3D scaffold-based in vitro cell culturing is a recent technological advancement in
cancer research bridging the gap between conventional 2D culture and in vivo tumours. The …
cancer research bridging the gap between conventional 2D culture and in vivo tumours. The …
Cancer stem cells and neuroblastoma: characteristics and therapeutic targeting options
The majority of embryonal tumors or childhood blastomas derive from pluripotent
progenitors or fetal stem cells that acquire cancer stem cell (CSC) properties: multipotency …
progenitors or fetal stem cells that acquire cancer stem cell (CSC) properties: multipotency …