Mechanisms of hair cell tuning

R Fettiplace, PA Fuchs - Annual review of physiology, 1999 - annualreviews.org
▪ Abstract Mechanosensory hair cells of the vertebrate inner ear contribute to acoustic tuning
through feedback processes involving voltage-gated channels in the basolateral membrane …

Prestin and the cochlear amplifier

P Dallos, J Zheng, MA Cheatham - The Journal of physiology, 2006 - Wiley Online Library
In non‐mammalian, hair cell‐bearing sense organs amplification is associated with
mechano‐electric transducer channels in the stereovilli (commonly called stereocilia) …

Cochlear outer hair cell electromotility enhances organ of Corti motion on a cycle-by-cycle basis at high frequencies in vivo

JB Dewey, A Altoè, CA Shera… - Proceedings of the …, 2021 - National Acad Sciences
Mammalian hearing depends on an amplification process involving prestin, a voltage-
sensitive motor protein that enables cochlear outer hair cells (OHCs) to change length and …

[HTML][HTML] Prestin-driven cochlear amplification is not limited by the outer hair cell membrane time constant

SL Johnson, M Beurg, W Marcotti, R Fettiplace - Neuron, 2011 - cell.com
Outer hair cells (OHCs) provide amplification in the mammalian cochlea using somatic force
generation underpinned by voltage-dependent conformational changes of the motor protein …

[图书][B] From sound to synapse: physiology of the mammalian ear

CD Geisler - 1998 - books.google.com
This comprehensive introduction to the functions of the mammalian ear describes the major
steps by which sound is transformed into nerve impulses. The author leads the reader along …

Limiting dynamics of high-frequency electromechanical transduction of outer hair cells

G Frank, W Hemmert… - Proceedings of the …, 1999 - National Acad Sciences
High-frequency resolution is one of the salient features of peripheral sound processing in
the mammalian cochlea. The sensitivity originates in the active amplification of the travelling …

The remarkable cochlear amplifier

J Ashmore, P Avan, WE Brownell, P Dallos, K Dierkes… - Hearing research, 2010 - Elsevier
This composite article is intended to give the experts in the field of cochlear mechanics an
opportunity to voice their personal opinion on the one mechanism they believe dominates …

Active hair-bundle movements can amplify a hair cell's response to oscillatory mechanical stimuli

P Martin, AJ Hudspeth - Proceedings of the National …, 1999 - National Acad Sciences
To enhance their mechanical sensitivity and frequency selectivity, hair cells amplify the
mechanical stimuli to which they respond. Although cell-body contractions of outer hair cells …

Force generation by mammalian hair bundles supports a role in cochlear amplification

HJ Kennedy, AC Crawford, R Fettiplace - Nature, 2005 - nature.com
It is generally accepted that the acute sensitivity and frequency discrimination of mammalian
hearing requires active mechanical amplification of the sound stimulus within the cochlea …

Resonant tectorial membrane motion in the inner ear: its crucial role in frequency tuning.

AW Gummer, W Hemmert… - Proceedings of the …, 1996 - National Acad Sciences
The tectorial membrane has long been postulated as playing a role in the exquisite
sensitivity of the cochlea. In particular, it has been proposed that the tectorial membrane …