Introduction Breast cancer (BC) accounts for the majority of cancers among the female
population. Anomalous activation of various signaling pathways has become an issue of …

Metastasis is crucial for the mortality of non-small cell lung carcinoma (NSCLC) patients. The
epithelial–mesenchymal transition (EMT) plays a critical role in regulating tumor metastasis …

Recently, nucleic acid drugs have been considered as promising candidates in treatment of
various diseases, especially cancer. Because of developing resistance to conventional …

Protein lysine succinylation (Ksucc) represents an important regulatory mechanism of tumor
development. In this work, the difference of protein Ksucc between HCMEC/D3 co-cultured …

In tissue engineering, cell origin is important to ensure outcome quality. However, the impact
of the cell type chosen for seeding in a biocompatible matrix has been less investigated …

Objective Methylation of the promoters of SHOX2 and RASSF1A are potentially informative
biomarkers for the diagnosis of early lung adenocarcinoma (LUAD). Abnormal methylation …

Emerging evidence has indicated that long noncoding RNAs (lncRNAs) are potential
biomarkers and play crucial roles in cancer development. However, the functions and …

The transcription factor SHOX2 gene is critical in regulating gene expression and the
development of tumors, but its biological role in prostate cancer (PCa) remains unclear. In …

Methylation of the promoters of SHOX2 and RASSF1A (LungMe®) exhibits promise as a
potential molecular biomarker for diagnosing lung cancer. This study sought to assess the …

Hypoxia spontaneously forms in the interior of glioma tissues and regulates the expression
of various genes. However, the status of hypoxia-driven genes in glioma tissues is not …