The gut barrier plays a crucial role by spatially compartmentalizing bacteria to the lumen
through the production of secreted mucus and is fortified by the production of secretory IgA …

Immunoglobulin A (IgA) plays a key role in defending mucosal surfaces against attack by
infectious microorganisms. Such sites present a major site of susceptibility due to their vast …

Antibodies secreted at the mucosal surface play an integral role in immune defense by
serving to neutralize the pathogen and promote its elimination at the site of entry. Secretory …

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Secretory IgA (SIgA) plays an important role in the protection and homeostatic regulation of
intestinal, respiratory, and urogenital mucosal epithelia separating the outside environment …

Recent advances of rotavirus (RV) basic and applied research are reviewed. They consist of
determination of the RV particle structure and functions of structural proteins, classification …

The intestinal mucosa contains the largest population of antibody-secreting plasma cells in
the body, and in humans several grams of secretory immunoglobulin A (SIgA) are released …

The production of immunoglobulin A (IgA) in mammals exceeds all other isotypes, and it is
mostly exported across mucous membranes. The discovery of IgA and the realization that it …

The gastrointestinal tract houses millions of microbes, and thus has evolved several host
defense mechanisms to keep them at bay, and prevent their entry into the host. One such …

Neutralizing antibodies are crucial for vaccine-mediated protection against viral diseases.
They probably act, in most cases, by blunting the infection, which is then resolved by cellular …