Anhedonia is considered a core feature of major depressive disorder, and the dopamine
system plays a pivotal role in the hedonic deficits described in this disorder. Dopaminergic …

There is increasing interest among functional neurosurgeons in the potential for novel
therapies to impact upon diseases beyond movement disorders and pain. A target of …

En este trabajo, se aborda la importancia de las emociones en el aprendizaje a partir de
investigaciones llevadas a cabo al respecto en el campo de la neurociencia y la psicología …

Research into the comorbidity between emotional psychopathology and cigarette smoking
has often focused upon anxiety and depression's manifest symptoms and syndromes, with …

Reward contains separable psychological components of learning, incentive motivation and
pleasure. Most computational models have focused only on the learning component of …

The capacity to predict future events permits a creature to detect, model, and manipulate the
causal structure of its interactions with its environment. Behavioral experiments suggest that …

This paper presents a biopsychological theory of drug addiction, the 'Incentive-Sensitization
Theory'. The theory addresses three fundamental questions. The first is: why do addicts …

Emotions seem to arise ultimately from hard-wired neural circuits in the visceral-limbic brain
that facilitate diverse and adaptive behavioral and physiological responses to major classes …

Schultz, Wolfram. Predictive reward signal of dopamine neurons. J. Neurophysiol. 80: 1–27,
1998. The effects of lesions, receptor blocking, electrical self-stimulation, and drugs of abuse …

What roles do mesolimbic and neostriatal dopamine systems play in reward? Do they
mediate the hedonic impact of rewarding stimuli? Do they mediate hedonic reward learning …