The amyloid-β pathway in Alzheimer's disease
Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …
Bee venom: Overview of main compounds and bioactivities for therapeutic interests
R Wehbe, J Frangieh, M Rima, D El Obeid, JM Sabatier… - Molecules, 2019 - mdpi.com
Apitherapy is an alternate therapy that relies on the usage of honeybee products, most
importantly bee venom for the treatment of many human diseases. The venom can be …
importantly bee venom for the treatment of many human diseases. The venom can be …
[HTML][HTML] Is Alzheimer's disease a type 3 diabetes? A critical appraisal
R Kandimalla, V Thirumala, PH Reddy - Biochimica et Biophysica Acta …, 2017 - Elsevier
Recently researchers proposed the term 'Type-3-Diabetes' for Alzheimer's disease (ad)
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …
Impact of HMGB1, RAGE, and TLR4 in Alzheimer's disease (AD): from risk factors to therapeutic targeting
Alzheimer's disease (AD) is a devastating neurodegenerative disorder and a leading cause
of dementia, with accumulation of amyloid-beta (Aβ) and neurofibrillary tangles (NFTs) as …
of dementia, with accumulation of amyloid-beta (Aβ) and neurofibrillary tangles (NFTs) as …
Astrocyte senescence: evidence and significance
J Cohen, C Torres - Aging cell, 2019 - Wiley Online Library
Astrocytes participate in numerous aspects of central nervous system (CNS) physiology
ranging from ion balance to metabolism, and disruption of their physiological roles can …
ranging from ion balance to metabolism, and disruption of their physiological roles can …
Alzheimer's disease and type 2 diabetes: a critical assessment of the shared pathological traits
S Chatterjee, A Mudher - Frontiers in neuroscience, 2018 - frontiersin.org
Alzheimer's disease (AD) and Type 2 Diabetes Mellitus (T2DM) are two of the most
prevalent diseases in the elderly population worldwide. A growing body of epidemiological …
prevalent diseases in the elderly population worldwide. A growing body of epidemiological …
Transcriptomic profiling of microglia and astrocytes throughout aging
J Pan, N Ma, B Yu, W Zhang, J Wan - Journal of Neuroinflammation, 2020 - Springer
Background Activation of microglia and astrocytes, a prominent hallmark of both aging and
Alzheimer's disease (AD), has been suggested to contribute to aging and AD progression …
Alzheimer's disease (AD), has been suggested to contribute to aging and AD progression …
Phospholipids of animal and marine origin: Structure, function, and anti-inflammatory properties
In this review paper, the latest literature on the functional properties of phospholipids in
relation to inflammation and inflammation-related disorders has been critically appraised …
relation to inflammation and inflammation-related disorders has been critically appraised …
Neuroinflammation as a factor of neurodegenerative disease: thalidomide analogs as treatments
YJ Jung, D Tweedie, MT Scerba… - Frontiers in Cell and …, 2019 - frontiersin.org
Neuroinflammation is initiated when glial cells, mainly microglia, are activated by threats to
the neural environment, such as pathogen infiltration or neuronal injury. Although …
the neural environment, such as pathogen infiltration or neuronal injury. Although …
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers
More than 20 genetic loci have been associated with risk for Alzheimer's disease (AD), but
reported genome-wide significant loci do not account for all the estimated heritability and …
reported genome-wide significant loci do not account for all the estimated heritability and …