Plasmacytoid dendritic cells (pDCs) are a unique DC subset that specializes in the
production of type I interferons (IFNs). pDCs promote antiviral immune responses and have …

Cells engaging in inflammation undergo drastic changes of their transcriptomes. In order to
tailor these alterations in gene expression to the requirements of the inflammatory process …

Probiotics can effectively improve ulcerative colitis (UC), but the mechanism is still unclear.
Here, shotgun metagenome and transcriptome analyses were performed to explore the …

The intestinal mucosa is a physiological barrier for most microbes, including both
commensal bacteria and invading pathogens. Under homeostatic conditions …

Probiotics have shown good efficacy in the prevention of ulcerative colitis (UC), but the
specific mechanism remains unclear. Therefore, shotgun metagenomic and transcriptome …

Oral antigen administration to induce regulatory T cells (Treg) takes advantage of regulatory
mechanisms that the gastrointestinal tract utilizes to promote unresponsiveness against food …

The gut represents a potential entry site for a wide range of pathogens including protozoa,
bacteria, viruses, or fungi. Consequently, it is protected by one of the largest and most …

Life-threatening fungal infections have risen sharply in recent years, owing to the advances
and intensity of medical care that may blunt immunity in patients. This emerging crisis has …

Plasmacytoid dendritic cells (pDCs) rapidly produce type I interferon (IFN-I) in response to
viruses and are essential for antiviral immune responses. Although related to classical DCs …

Dendritic cells (DCs) and monocytes develop from a series of bone-marrow–resident
progenitors in which lineage potential is regulated by distinct transcription factors. Zeb2 is an …