Morphological, cellular, and molecular basis of brain infection in COVID-19 patients

F Crunfli, VC Carregari, FP Veras… - Proceedings of the …, 2022 - National Acad Sciences
Although increasing evidence confirms neuropsychiatric manifestations associated mainly
with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently …

Leveraging machine learning for gaining neurobiological and nosological insights in psychiatric research

J Chen, KR Patil, BTT Yeo, SB Eickhoff - Biological psychiatry, 2023 - Elsevier
Much attention is currently devoted to developing diagnostic classifiers for mental disorders.
Complementing these efforts, we highlight the potential of machine learning to gain …

[HTML][HTML] Lessons learned from parsing genetic risk for schizophrenia into biological pathways

G Pergola, N Penzel, L Sportelli, A Bertolino - Biological Psychiatry, 2023 - Elsevier
The clinically heterogeneous presentation of schizophrenia is compounded by the
heterogeneity of risk factors and neurobiological correlates of the disorder. Genome-wide …

Neurophysiological signatures of cortical micro-architecture

G Shafiei, BD Fulcher, B Voytek… - Nature …, 2023 - nature.com
Systematic spatial variation in micro-architecture is observed across the cortex. These micro-
architectural gradients are reflected in neural activity, which can be captured by …

Traumatic stress load and stressor reactivity score associated with accelerated gray matter maturation in youths indexed by normative models

TY Wong, TM Moore, J Seidlitz, KSL Yuen… - Molecular …, 2023 - nature.com
Understanding how traumatic stress affects typical brain development during adolescence is
critical to elucidate underlying mechanisms related to both maladaptive functioning and …

Mapping human brain charts cross-sectionally and longitudinally

MA Di Biase, YE Tian, RAI Bethlehem… - Proceedings of the …, 2023 - National Acad Sciences
Brain scans acquired across large, age-diverse cohorts have facilitated recent progress in
establishing normative brain aging charts. Here, we ask the critical question of whether …

[HTML][HTML] Spatial transcriptomic patterns underlying amyloid-β and tau pathology are associated with cognitive dysfunction in Alzheimer's disease

M Yu, SL Risacher, KT Nho, Q Wen, AL Oblak… - Cell reports, 2024 - cell.com
Amyloid-β (Aβ) and tau proteins accumulate within distinct neuronal systems in Alzheimer's
disease (AD). Although it is not clear why certain brain regions are more vulnerable to Aβ …

The role of glial cells in mental illness: a systematic review on astroglia and microglia as potential players in schizophrenia and its cognitive and emotional aspects

D Laricchiuta, M Papi, D Decandia… - Frontiers in Cellular …, 2024 - frontiersin.org
Schizophrenia is a complex and severe mental disorder that affects approximately 1% of the
global population. It is characterized by a wide range of symptoms, including delusions …

Neuroanatomical, transcriptomic, and molecular correlates of math ability and their prognostic value for predicting learning outcomes

J Liu, K Supekar, D El-Said, C de Los Angeles… - Science …, 2024 - science.org
Foundational mathematical abilities, acquired in early childhood, are essential for success in
our technology-driven society. Yet, the neurobiological mechanisms underlying individual …

Compressed primary‐to‐transmodal gradient is accompanied with subcortical alterations and linked to neurotransmitters and cellular signatures in major depressive …

Y Xiao, L Zhao, X Zang, SW Xue - Human Brain Mapping, 2023 - Wiley Online Library
Major depressive disorder (MDD) has been shown to involve widespread changes in low‐
level sensorimotor and higher‐level cognitive functions. Recent research found that a …