The role of clinical trial participation in cancer research: barriers, evidence, and strategies
JM Unger, E Cook, E Tai, A Bleyer - American Society of Clinical …, 2016 - ascopubs.org
Fewer than one in 20 adult patients with cancer enroll in cancer clinical trials. Although
barriers to trial participation have been the subject of frequent study, the rate of trial …
barriers to trial participation have been the subject of frequent study, the rate of trial …
Adolescent and young adult oncology—past, present, and future
There are nearly 70,000 new cancer diagnoses made annually in adolescents and young
adults (AYAs) in the United States. Historically, AYA patients with cancer, aged 15 to 39 …
adults (AYAs) in the United States. Historically, AYA patients with cancer, aged 15 to 39 …
Innovations in research and clinical care using patient‐generated health data
Patient‐generated health data (PGHD), or health‐related data gathered from patients to help
address a health concern, are used increasingly in oncology to make regulatory decisions …
address a health concern, are used increasingly in oncology to make regulatory decisions …
Real-world safety and efficacy of consolidation durvalumab after chemoradiation therapy for stage III non-small cell lung cancer: A systematic review and meta …
Y Wang, T Zhang, Y Huang, W Li, J Zhao… - International Journal of …, 2022 - Elsevier
Purpose Consolidation durvalumab after chemoradiation therapy (CRT) has improved
patient outcomes in stage III non-small cell lung cancer (NSCLC) since the practice …
patient outcomes in stage III non-small cell lung cancer (NSCLC) since the practice …
Leveraging external data in the design and analysis of clinical trials in neuro-oncology
Integration of external control data, with patient-level information, in clinical trials has the
potential to accelerate the development of new treatments in neuro-oncology by …
potential to accelerate the development of new treatments in neuro-oncology by …
[HTML][HTML] Comparison of population-based observational studies with randomized trials in oncology
PURPOSE Comparative efficacy research performed using population registries can be
subject to significant bias. There is an absence of objective data demonstrating factors that …
subject to significant bias. There is an absence of objective data demonstrating factors that …
Geographic distribution and survival outcomes for rural patients with cancer treated in clinical trials
JM Unger, A Moseley, B Symington… - JAMA Network …, 2018 - jamanetwork.com
Importance Studies showing that patients with cancer from rural areas have worse outcomes
than their urban counterparts have relied on cancer population data and did not account for …
than their urban counterparts have relied on cancer population data and did not account for …
Association of patient comorbid conditions with cancer clinical trial participation
Importance The American Society of Clinical Oncology (ASCO), Friends of Cancer
Research, and the US Food and Drug Administration recently recommended modernizing …
Research, and the US Food and Drug Administration recently recommended modernizing …
Use and effectiveness of intraperitoneal chemotherapy for treatment of ovarian cancer
AA Wright, A Cronin, DE Milne, MA Bookman… - Journal of Clinical …, 2015 - ascopubs.org
Purpose A 2006 randomized trial demonstrated a 16-month survival benefit with
intraperitoneal and intravenous (IP/IV) chemotherapy administered to patients who had …
intraperitoneal and intravenous (IP/IV) chemotherapy administered to patients who had …
Association between body mass index and cancer survival in a pooled analysis of 22 clinical trials
H Greenlee, JM Unger, M LeBlanc, S Ramsey… - … , biomarkers & prevention, 2017 - AACR
Background: Data are inconsistent on the association between body mass index (BMI) at
time of cancer diagnosis and prognosis. We used data from 22 clinical treatment trials to …
time of cancer diagnosis and prognosis. We used data from 22 clinical treatment trials to …