Single-cell transcriptomics has broadened our understanding of cellular diversity and gene
expression dynamics in healthy and diseased tissues. Recently, spatial transcriptomics has …

Increasing evidence supports a central role of the immune system in sepsis, but the current
view of how sepsis affects immunity, and vice versa, is still rudimentary. The European …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …

Environmental genotoxic factors pose a challenge to the genomic integrity of epithelial cells
at barrier surfaces that separate host organisms from the environment. They can induce …

Mass cytometry has revolutionized immunophenotyping, particularly in exploratory settings
where simultaneous breadth and depth of characterization of immune populations is needed …

Cryopreservation of semen and artificial insemination have an important, positive impact on
cattle production, and product quality. Through the use of cryopreserved semen and artificial …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Failure to make adaptive immune responses is a hallmark of aging. Reduced B cell function
leads to poor vaccination efficacy and a high prevalence of infections in the elderly. Here we …

Multiple sclerosis is a chronic inflammatory, demyelinating disease, although it has been
suggested that in the progressive late phase, inflammatory lesion activity declines. We …