After the unexpected arrival of West Nile virus (WNV) in the United States in 1999, the
mosquito-borne virus quickly spread throughout North America. Over the past 20 years …

Emerging and reemerging infectious diseases have a strong negative impact on public
health. However, because many of these pathogens must be handled in biosafety level, 3 or …

Zika virus (ZIKV) has recently emerged as a pandemic associated with severe
neuropathology in newborns and adults. There are no ZIKV-specific treatments or …

Zika virus (ZIKV) was identified as a cause of congenital disease during the explosive
outbreak in the Americas and Caribbean that began in 2015. Because of the ongoing fetal …

Antibodies to Zika virus (ZIKV) can be protective. To examine the antibody response in
individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil …

Severe acute respiratory syndrome (SARS) is caused by a coronavirus (SARS-CoV) and
has the potential to threaten global public health and socioeconomic stability. Evidence of …

Flaviviruses infect hundreds of millions of people annually, and no antiviral therapy is
available,. We performed a genome-wide CRISPR/Cas9-based screen to identify host …

Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4)
specifically bind phosphatidylserine (PS). TIM1 has been proposed to serve as a cellular …

Human cytomegalovirus (HCMV) is a widely circulating pathogen that causes severe
disease in immunocompromised patients and infected fetuses. By immortalizing memory B …

Four dengue virus serotypes (DENV1-4) circulate globally, causing more human illness than
any other arthropod-borne virus. Dengue can present as a range of clinical manifestations …