Following a diagnosis of breast cancer, the most immediate challenges in patient
management are the determination of prognosis and identification of the most appropriate …

Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …

Purpose: To identify tumor-derived exosomal biomarkers that are able to discriminate
between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in …

Efficient patient management relies on early diagnosis of disease and monitoring of
treatment. In this regard, much effort has been made to find informative, blood-based …

Purpose Exosomal microRNAs (miRNAs) have been attracting major interest as potential
diagnostic biomarkers of cancer. The aim of this study was to characterize the miRNA …

Metastasis is associated with poor prognosis in breast cancer patients. Not all cancer cells
within a tumor are capable of metastasizing. The microRNA-200 (miR-200) family, which …

Diabetes mellitus is characterized by insulin secretion from pancreatic β cells that is
insufficient to maintain blood glucose homeostasis. Autoimmune destruction of β cells …

Breast cancer affects approximately 12% women worldwide and results in 14% of all cancer-
related fatalities. Breast cancer is commonly categorized into one of four main subtypes …

MicroRNAs (miRNAs) are a large family of small non-coding RNAs that negatively regulate
protein-coding gene expression post-transcriptionally via base pairing between the 5 …

Extracellular vesicles (EVs) produced by cancer cells function as a unique form of
intercellular communication that can promote cell growth and survival, help shape the tumor …