Candida albicans-Biology, molecular characterization, pathogenicity, and advances in diagnosis and control–An update

M Dadar, R Tiwari, K Karthik, S Chakraborty… - Microbial …, 2018 - Elsevier
Candida albicans is an emerging multidrug-resistant fungal pathogen representing an
important source of invasive disease in humans and generating high healthcare costs …

Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans

S Biswas, P Van Dijck, A Datta - Microbiology and molecular …, 2007 - Am Soc Microbiol
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives

TJ Sharpton, JE Stajich, SD Rounsley… - Genome …, 2009 - genome.cshlp.org
While most Ascomycetes tend to associate principally with plants, the dimorphic fungi
Coccidioides immitis and Coccidioides posadasii are primary pathogens of …

ALTERNATIVE CANDIDA ALBICANS LIFESTYLES: Growth on Surfaces

CA Kumamoto, MD Vinces - Annu. Rev. Microbiol., 2005 - annualreviews.org
Candida albicans, an opportunistic fungal pathogen, causes a wide variety of human
diseases such as oral thrush and disseminated candidiasis. Many aspects of C. albicans …

The metabolic basis of Candida albicans morphogenesis and quorum sensing

TL Han, RD Cannon, SG Villas-Bôas - Fungal Genetics and Biology, 2011 - Elsevier
Candida albicans is a polymorphic fungus that has the ability to rapidly switch between
yeast and filamentous forms. The morphological transition appears to be a critical virulence …

The eukaryotic plasma membrane as a nutrient-sensing device

I Holsbeeks, O Lagatie, A Van Nuland… - Trends in biochemical …, 2004 - cell.com
In eukaryotic cells, G-protein-coupled receptors (GPCRs), non-transporting nutrient carrier
homologues and active nutrient carriers have been recently shown to function as sensors …

Discovery of novel fungal lanosterol 14α-demethylase (CYP51)/histone deacetylase dual inhibitors to treat azole-resistant candidiasis

G Han, N Liu, C Li, J Tu, Z Li… - Journal of medicinal …, 2020 - ACS Publications
Invasive fungal infections (particularly candidiasis) are emerging as severe infectious
diseases worldwide. Because of serious antifungal drug resistance, therapeutic efficacy of …

[HTML][HTML] Integrated proteomics and genomics strategies bring new insight into Candida albicans response upon macrophage interaction

E Fernández-Arenas, V Cabezón, C Bermejo… - Molecular & Cellular …, 2007 - ASBMB
The interaction of Candida albicans with macrophages is considered a crucial step in the
development of an adequate immune response in systemic candidiasis. An in vitro model of …

[HTML][HTML] Role of amino acid metabolism in the virulence of human pathogenic fungi

E Garbe, S Vylkova - Current Clinical Microbiology Reports, 2019 - Springer
Abstract Purpose of the Review The success of Candida albicans, Aspergillus fumigatus,
and Cryptococcus neoformans as fungal pathogens depends on their rapid adaptation to …

[HTML][HTML] Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis

S Puri, R Kumar, S Chadha, S Tati, HR Conti, B Hube… - PloS one, 2012 - journals.plos.org
Perception of external stimuli and generation of an appropriate response are crucial for host
colonization by pathogens. In pathogenic fungi, mitogen activated protein kinase (MAPK) …