Digital twins for tissue culture techniques—concepts, expectations, and state of the art
Techniques to provide in vitro tissue culture have undergone significant changes during the
last decades, and current applications involve interactions of cells and organoids, three …
last decades, and current applications involve interactions of cells and organoids, three …
Design, fabrication, and characterization of a multimodal reconfigurable bioreactor for bone tissue engineering
M Montorsi, GG Genchi, D De Pasquale… - Biotechnology and …, 2022 - Wiley Online Library
In the past decades, bone tissue engineering developed and exploited many typologies of
bioreactors, which, besides providing proper culture conditions, aimed at integrating those …
bioreactors, which, besides providing proper culture conditions, aimed at integrating those …
Computer-aided engineering and additive manufacturing for bioreactors in tissue engineering: State of the art and perspectives
Two main challenges are currently present in the healthcare world, ie, the limitations given
by transplantation and the need to have available 3D in vitro models. In this context …
by transplantation and the need to have available 3D in vitro models. In this context …
Direct coupled electrical stimulation towards improved osteogenic differentiation of human mesenchymal stem/stromal cells: a comparative study of different protocols
Electrical stimulation (ES) has been described as a promising tool for bone tissue
engineering, being known to promote vital cellular processes such as cell proliferation …
engineering, being known to promote vital cellular processes such as cell proliferation …
JANUS: an open-source 3D printable perfusion bioreactor and numerical model-based design strategy for tissue engineering
Bioreactors have been employed in tissue engineering to sustain longer and larger cell
cultures, managing nutrient transfer and waste removal. Multiple designs have been …
cultures, managing nutrient transfer and waste removal. Multiple designs have been …
Medicated multi-targeted alginate-based dressings for potential treatment of mixed bacterial-fungal infections in diabetic foot ulcers
Recently developed medicated dressings target either bacterial or fungal infection only,
which is not effective for the treatment of mixed infections common in diabetic foot ulcers …
which is not effective for the treatment of mixed infections common in diabetic foot ulcers …
CyMAD bioreactor: A cyclic magnetic actuation device for magnetically mediated mechanical stimulation of 3D bioprinted hydrogel scaffolds
C Czichy, D Kilian, TC Wang, S Günther, A Lode… - Journal of the …, 2022 - Elsevier
Mechanical stimulation of bioprinted constructs can enhance the differentiation of cells
within these scaffolds, such as driving chondrocytes towards cartilage tissue substitutes. In …
within these scaffolds, such as driving chondrocytes towards cartilage tissue substitutes. In …
Synergy between 3D-extruded electroconductive scaffolds and electrical stimulation to improve bone tissue engineering strategies
In this work, we propose a simple, reliable, and versatile strategy to create 3D
electroconductive scaffolds suitable for bone tissue engineering (TE) applications with …
electroconductive scaffolds suitable for bone tissue engineering (TE) applications with …
Computational and experimental investigation of the combined effect of various 3d scaffolds and bioreactor stimulation on human cells' feedback
Computational methods were combined with an experimental setup in order to investigate
the response of human umbilical cord stem cells to 3D electrospun and printed scaffolds …
the response of human umbilical cord stem cells to 3D electrospun and printed scaffolds …
A novel approach for design and manufacturing of curvature-featuring scaffolds for osteochondral repair
Osteochondral (OC) defects affect both articular cartilage and the underlying subchondral
bone. Due to limitations in the cartilage tissue's self-healing capabilities, OC defects exhibit …
bone. Due to limitations in the cartilage tissue's self-healing capabilities, OC defects exhibit …