Central nervous system pathways targeted by amylin in the regulation of food intake

MK Hankir, C Le Foll - Biochimie, 2024 - Elsevier
Amylin is a peptide hormone co-released with insulin from pancreatic β-cells during a meal
and primarily serves to promote satiation. While the caudal hindbrain was originally …

An endogenous GLP-1 circuit engages VTA GABA neurons to regulate mesolimbic dopamine neurons and attenuate cocaine seeking

R Merkel, N Hernandez, V Weir, Y Zhang, MT Rich… - bioRxiv, 2024 - biorxiv.org
Recent studies show that systemic administration of a glucagon-like peptide-1 receptor (GLP-
1R) agonist is sufficient to attenuate the reinstatement of cocaine-seeking behavior, an …

[HTML][HTML] Ventral tegmental area amylin/calcitonin receptor signaling suppresses feeding and weight gain in female rats

TJ Gustafson, LE McGrath, MR Hayes… - Neuroscience …, 2024 - Elsevier
The pancreatic peptide amylin promotes negative energy balance in part through activation
of amylin receptors (AmyRs) expressed in the ventral tegmental area (VTA), but studies have …

Amylin, the Prefrontal Cortex, and Impulsive Eating

TA Lutz - Biological Psychiatry, 2024 - biologicalpsychiatryjournal.com
The modern world faces an exploding obesity epidemic. Many years of intensive research
have led to the development of gut hormone analogues that for the first time seem to offer a …

Disentangling the Effects of Orosensory Versus Postingestive Feedback From Palatable Food Consumption on Amylin Signaling in the Ventral Tegmental Area

SI Martin - 2024 - search.proquest.com
Obesity has steadily been increasing in the United States. A promising candidate for non-
invasive pharmacological treatments is the hormone amylin due to its promotion of negative …