Genomic instability is a primary cause and fundamental feature of human cancer. However,
all cancer cell genotypes generally translate into several common pathophysiological …

Membrane potential (Vm), the voltage across the plasma membrane, arises because of the
presence of different ion channels/transporters with specific ion selectivity and permeability …

The human ether-a-go-go related gene (hERG) encodes the pore-forming subunit of the
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …

Potassium channels are transmembrane proteins that selectively facilitate the flow of
potassium ions down an electrochemical gradient. These molecules have been studied in …

The human genome encodes 40 voltage-gated K+ channels (KV), which are involved in
diverse physiological processes ranging from repolarization of neuronal and cardiac action …

Venomous animals have evolved a vast array of peptide toxins for prey capture and
defence. These peptides are directed against a wide variety of pharmacological targets …

All cells possess long-term, steady-state voltage gradients across the plasma membrane.
These transmembrane potentials arise from the combined activity of numerous ion channels …

Membrane ion channels are essential for cell proliferation and appear to have a role in the
development of cancer. This has initially been demonstrated for potassium channels and is …

We have investigated the possible implication of the cell cycle‐regulated K+ channel ether à
go‐go (EAG) in cell proliferation and transformation. We show that transfection of EAG into …

It is commonly accepted that cells require K+ channels to proliferate. The role (s) of K+
channels in the process is, however, poorly understood. Cloning of K+ channel genes …