Social interaction is known to be the main source of stress in human beings, which explains
the translational importance of this research in animals. Evidence reported over the last …

Although developed from a common antecedent, conditioned place preference (CPP) and
intravenous drug self-administration (SA) represent different behavioral paradigms, each …

Astrocytes are ubiquitous CNS cells that support tissue homeostasis through ion buffering,
neurotransmitter recycling, and regulation of CNS vasculature. Yet, despite the essential …

Adverse social experiences during adolescence are associated with the appearance of
mental illness in adulthood. Social defeat (SD) is an ethologically valid murine model to …

The neuropeptide oxytocin (OXT) plays a critical role in the regulation of social and
emotional behaviors. OXT plays a role in stress response and in drug reward, but to date no …

The experience of social stress during adolescence is associated with higher vulnerability to
drug use. Increases in the acquisition of cocaine self-administration, in the escalation of …

Social interaction with unfamiliar individuals is necessary for species-preserving behaviors
such as finding mates and establishing social groups. However, social conflict is a potential …

The lipid-derived messenger oleoylethanolamide (OEA) has been involved in multiple
physiological functions including metabolism and the immune response. More recently, OEA …

Using the social defeat (SD) model, numerous studies have shown that stressed mice
display an enhanced response to the motivational effects of cocaine in the self …

Large preclinical evidence shows that exposure to social defeat (SD) increases vulnerability
to drug abuse, increasing the consumption of ethanol. However, not all subjects are equally …