Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Neuronal migration in the CNS during development and disease: insights from in vivo and in vitro models

IY Buchsbaum, S Cappello - Development, 2019 - journals.biologists.com
Neuronal migration is a fundamental process that governs embryonic brain development. As
such, mutations that affect essential neuronal migration processes lead to severe brain …

Cellular and molecular mechanisms controlling the migration of neocortical interneurons

O Marín - European Journal of Neuroscience, 2013 - Wiley Online Library
The discovery, approximately 15 years ago, that cortical GABA ergic interneurons originate
outside the pallium has revolutionized our understanding of the development of the cerebral …

POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex

MH Dominguez, AE Ayoub, P Rakic - Cerebral cortex, 2013 - academic.oup.com
The upper layers (II–IV) are the most prominent distinguishing feature of mammalian
neocortex compared with avian or reptilian dorsal cortex, and are vastly expanded in …

Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development

S Cappello, MJ Gray, C Badouel, S Lange… - Nature …, 2013 - nature.com
The regulated proliferation and differentiation of neural stem cells before the generation and
migration of neurons in the cerebral cortex are central aspects of mammalian development …

The multipolar stage and disruptions in neuronal migration

JJ LoTurco, J Bai - Trends in neurosciences, 2006 - cell.com
The genetic basis is now known for several disorders of neuronal migration in the
developing cerebral cortex. Identification of the cellular processes mediated by the …

Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons

Y Shen, H Qin, J Chen, L Mou, Y He, Y Yan… - Journal of Cell …, 2016 - rupress.org
Astrocytes are critical in synapse development, and their dysfunction in crucial
developmental stages leads to serious neurodevelopmental diseases, including seizures …

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate

G Miyoshi, G Fishell - Neuron, 2012 - cell.com
Pyramidal cells of the cerebral cortex are born in the ventricular zone and migrate through
the intermediate zone to enter into the cortical plate. In the intermediate zone, these …

Stage-Specific Modulation of Cortical Neuronal Development by Mmu-miR-134

P Gaughwin, M Ciesla, H Yang, B Lim… - Cerebral cortex, 2011 - academic.oup.com
To realize the potential of microRNAs (miRs) as fine-tuning regulators of embryonic
neuronal differentiation, it is critical to define their developmental function. Mmu-miR-134 …

A method for stable transgenesis of radial glia lineage in rat neocortex by piggyBac mediated transposition

F Chen, J LoTurco - Journal of neuroscience methods, 2012 - Elsevier
Methods that combine lineage tracing with cellular transgenesis are needed in order to
determine mechanisms that specify neural cell types. Currently available methods include …