The Calcium-Sensing Receptor (CaSR) is a member of the class C of G-proteins coupled
receptors (GPCRs), it plays a pivotal role in calcium homeostasis by directly controlling …

The calcium-sensing receptor (CaSR) plays a pivotal role in systemic calcium metabolism by
regulating parathyroid hormone secretion and urinary calcium excretion. The diseases …

Abstract Context Immune checkpoint inhibitors (ICIs), such as programmed cell death
protein-1 (PD-1), programmed cell death protein-ligand 1 (PD-L1), and cytotoxic T …

This narrative report summarizes diagnostic criteria for hypoparathyroidism and describes
the clinical presentation and underlying genetic causes of the nonsurgical forms. We …

Context Patients with hypoparathyroidism are treated with vitamin D and calcium. PTH is an
emerging option because of its physiological action. It is important to assess the efficacy and …

Calcium is vital to many aspects of human biology. For example, calcium is involved in
intracellular and intercellular signal transmissions, muscular contraction, coagulation, and …

Summary Calcium (Ca 2+) is fundamental to organic life, and the ability to detect and
respond to changes in extracellular Ca 2+ ions (Ca 2+ o) is paramount to all living …

Résumé La parathormone (PTH), sécrétée par les parathyroïdes, est le principal régulateur
de l'homéostasie du calcium. L'hypoparathyroïdie (HypoPT), secondaire à une insuffisance …

Context Pathogenesis of idiopathic hypoparathyroidism (IH) is under investigation.
Abnormalities in central immune tolerance have yet not been investigated in this condition. T …