Ischaemic preconditioning of the brain, mechanisms and applications
HJ Steiger, D Hänggi - Acta Neurochirurgica, 2007 - Springer
Background. The concept of ischaemic preconditioning was introduced in the late 1980s.
The concept emerged that a brief subcritical ischaemic challenge could mobilize intrinsic …
The concept emerged that a brief subcritical ischaemic challenge could mobilize intrinsic …
Mitochondrial targets for volatile anesthetics against cardiac ischemia-reperfusion injury
Mitochondria are critical modulators of cell function and are increasingly recognized as
proximal sensors and effectors that ultimately determine the balance between cell survival …
proximal sensors and effectors that ultimately determine the balance between cell survival …
Sevoflurane preconditioning improves mitochondrial function and long-term neurologic sequelae after transient cerebral ischemia: role of mitochondrial permeability …
R Ye, Q Yang, X Kong, N Li, Y Zhang, J Han… - Critical care …, 2012 - journals.lww.com
Objective: Anesthetic preconditioning appears to be a viable strategy to treat ischemic
cerebral injury. Here we investigated 1) whether the protection conferred by sevoflurane …
cerebral injury. Here we investigated 1) whether the protection conferred by sevoflurane …
Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial KATP channel activation in isolated rat hearts
DK Song, Y Jang, JH Kim, KJ Chun… - Journal of Korean …, 2010 - synapse.koreamed.org
Polyphenol (-)-epigallocatechin gallate (EGCG), the most abundant catechin of green tea,
appears to attenuate myocardial ischemia/reperfusion injury. We investigated the …
appears to attenuate myocardial ischemia/reperfusion injury. We investigated the …
Sevoflurane mitigates shedding of hyaluronan from the coronary endothelium, also during ischemia/reperfusion: an ex vivo animal study
C Chen, D Chappell, T Annecke, P Conzen, M Jacob… - Hypoxia, 2016 - Taylor & Francis
Glycosaminoglycan hyaluronan (HA), a major constituent of the endothelial glycocalyx,
helps to maintain vascular integrity. Preconditioning the heart with volatile anesthetic agents …
helps to maintain vascular integrity. Preconditioning the heart with volatile anesthetic agents …
Mechanism of cardiac preconditioning with volatile anaesthetics
ZY Hu, J Liu - Anaesthesia and intensive care, 2009 - journals.sagepub.com
In recent years, there has been increased interest in the mechanisms involved in
anaesthetic-induced cardioprotection. It is not thoroughly understood how volatile …
anaesthetic-induced cardioprotection. It is not thoroughly understood how volatile …
Inhaled sevoflurane produces better delayed myocardial protection at 48 versus 24 hours after exposure
M Lutz, H Liu - Anesthesia & Analgesia, 2006 - journals.lww.com
IMPLICATIONS: A delayed window of volatile anesthetic preconditioning limits intracellular
Na+ and Ca+ 2, prevents the depletion of adenosine triphosphate, and improves function …
Na+ and Ca+ 2, prevents the depletion of adenosine triphosphate, and improves function …
Nuclear factor-κB inhibition provides additional protection against ischaemia/reperfusion injury in delayed sevoflurane preconditioning
MR Konia, S Schaefer, H Liu - European Journal of …, 2009 - journals.lww.com
Methods Hearts from 2-month-old male Fisher 344 rats were exposed to 25 min global
ischaemia followed by 60 min reperfusion. Rats were divided into four groups prior to I/R …
ischaemia followed by 60 min reperfusion. Rats were divided into four groups prior to I/R …
Activation of NF-κB is a critical element in the antiapoptotic effect of anesthetic preconditioning
X Lu, H Liu, L Wang, S Schaefer - American Journal of …, 2009 - journals.physiology.org
Anesthetic preconditioning (APC), defined as brief exposure to inhalational anesthetics
before cardiac ischemia-reperfusion (I/R), limits injury in both animal models and in humans …
before cardiac ischemia-reperfusion (I/R), limits injury in both animal models and in humans …
Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytes
GC Rodrigo, NJ Samani - American Journal of Physiology …, 2008 - journals.physiology.org
Current cellular models of ischemic preconditioning (IPC) rely on inducing preconditioning
in vitro and may not accurately represent complex pathways triggered by IPC in the intact …
in vitro and may not accurately represent complex pathways triggered by IPC in the intact …