Conspectus The oxindole scaffold is a privileged structural motif that is found in a variety of
bioactive targets and natural products. Moreover, derivatives of the oxindole structure are …

Metal-catalyzed regiodivergent reactions allow control over regioselectivity in the synthesis
of a wide range of organic products. Starting from the same material, it is possible to prepare …

Methods to functionalize arenes and heteroarenes in a site-selective manner are highly
sought after for rapidly constructing value-added molecules of medicinal, agrochemical, and …

Dialkylbiaryl phosphines are a valuable class of ligand for Pd-catalyzed amination reactions
and have been applied in a range of contexts. This perspective attempts to aid the reader in …

Brominated flame retardants (BFRs) are bromine-bearing hydrocarbons added or applied to
materials to increase their fire resistance. As thermal treatment and recycling are common …

Azine‐containing biaryls are ubiquitous scaffolds in many areas of chemistry, and efficient
methods for their synthesis are continually desired. Pyridine rings are prominent amongst …

The distortion/interaction model has been used to explain and predict reactivity in a variety
of reactions where more common explanations, such as steric and electronic factors, do not …

A Ni/photoredox dual catalytic cross-coupling is disclosed in which a diverse range of
(hetero) aryl bromides are used as electrophiles, with 1, 4-dihydropyridines serving as …

Two limiting mechanisms are possible for oxidative addition of (hetero) aryl (pseudo) halides
at Pd (0): a 3-centered concerted and a nucleophilic displacement mechanism. Until now …

Suzuki–Miyaura cross-coupling reactions of heteroaryl polyhalides with aryl boronates are
surveyed. Drawing on data from literature sources as well as bespoke searches of Pfizer's …