Liquid–liquid phase separation of biomacromolecules and its roles in metabolic diseases

Z Chen, Y Huai, W Mao, X Wang, K Ru, A Qian, H Yang - Cells, 2022 - mdpi.com
Liquid–liquid phase separation (LLPS) compartmentalizes and concentrates
biomacromolecules into liquid-like condensates, which underlies membraneless organelles …

Exploration of Organic Nanomaterials with Liquid-Phase Transmission Electron Microscopy

J Korpanty, NC Gianneschi - Accounts of chemical research, 2023 - ACS Publications
Conspectus Organic, soft materials with solution-phase nanoscale structures, such as
emulsions, hydrogels, and thermally responsive materials, are inherently difficult to directly …

Direct imaging of “Patch-Clasping” and relaxation in robust and flexible nanoparticle assemblies

A Kim, K Akkunuri, C Qian, L Yao, K Sun, Z Chen… - ACS …, 2023 - ACS Publications
Polymer patching on inorganic nanoparticles (NPs) enables multifunctionality and directed
self-assembly into nonclosely packed optical and mechanical metamaterials. However …

Ouzo effect examined at the nanoscale via direct observation of droplet nucleation and morphology

MA Vratsanos, W Xue, ND Rosenmann… - ACS Central …, 2023 - ACS Publications
Herein, we present the direct observation via liquid-phase transmission electron microscopy
(LPTEM) of the nucleation and growth pathways of structures formed by the so-called “ouzo …

Revealing microscopic dynamics: in situ liquid-phase TEM for live observations of soft materials and quantitative analysis via deep learning

Y Sun, X Zhang, R Huang, D Yang, J Kim, J Chen… - Nanoscale, 2024 - pubs.rsc.org
In various domains spanning materials synthesis, chemical catalysis, life sciences, and
energy materials, in situ transmission electron microscopy (TEM) methods exert a profound …

[HTML][HTML] Controlling self-assembling co-polymer coatings of hydrophilic polysaccharide substrates via co-polymer block length ratio

A Scacchi, K Hasheminejad, SJ Nikkhah… - Journal of Colloid and …, 2023 - Elsevier
Hypothesis The degree of polymerization of amphiphilic di-block co-polymers, which can be
varied with ease in computer simulations, provides a means to control self-assembling di …

Observing the Dynamics of an Electrochemically Driven Active Material with Liquid Electron Microscopy

W Gibson, JT Mulvey, S Das, S Selmani, JG Merham… - ACS …, 2024 - ACS Publications
Electrochemical liquid electron microscopy has revolutionized our understanding of
nanomaterial dynamics by allowing for direct observation of their electrochemical …

Direct visualization of polymerization-induced self-assembly of amphiphilic copolymers

V Jabbari, AH Phakatkar, A Amiri, A Ghorbani… - …, 2023 - ACS Publications
The ability to have precise control over the designed structure and properties of molecular
self-assemblies is critical for tailoring the quality and efficacy of their functionality, yet the …

[HTML][HTML] Correlating electrochemical stimulus to structural change in liquid electron microscopy videos using the structural dissimilarity metric

JT Mulvey, KP Iyer, T Ortega, JG Merham, Y Pivak… - Ultramicroscopy, 2024 - Elsevier
In-situ liquid cell transmission electron microscopy (LCTEM) with electrical biasing
capabilities has emerged as an invaluable tool for directly imaging electrode processes with …

Nanopipette dynamic microscopy unveils nano coffee ring

D Zhang, Y Shao, J Zhou, Q Zhan, Z Wen… - Proceedings of the …, 2024 - pnas.org
Liquid-phase electron microscopy (LP-EM) imaging has revolutionized our understanding of
nanosynthesis and assembly. However, the current closed geometry limits its application for …