Mining the plasma proteome for cancer biomarkers

SM Hanash, SJ Pitteri, VM Faca - Nature, 2008 - nature.com
Systematic searches for plasma proteins that are biological indicators, or biomarkers, for
cancer are underway. The difficulties caused by the complexity of biological-fluid proteomes …

Multiplexed protein measurement: technologies and applications of protein and antibody arrays

SF Kingsmore - Nature reviews Drug discovery, 2006 - nature.com
The ability to measure the abundance of many proteins precisely and simultaneously in
experimental samples is an important, recent advance for static and dynamic, as well as …

In pursuit of zero: polymer brushes that resist the adsorption of proteins

A Hucknall, S Rangarajan, A Chilkoti - Advanced Materials, 2009 - Wiley Online Library
Protein resistant or “non‐fouling” surfaces are of great interest for a variety of biomedical and
biotechnology applications. This article briefly reviews the development of protein resistant …

Human body fluid proteome analysis

S Hu, JA Loo, DT Wong - Proteomics, 2006 - Wiley Online Library
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

A systematic review of the association between circulating concentrations of C reactive protein and cancer

K Heikkilä, S Ebrahim, DA Lawlor - Journal of Epidemiology & …, 2007 - jech.bmj.com
The objective of this study was to review and summarise the published evidence for an
association between circulating concentrations of C reactive protein (CRP) and cancer …

Serum amyloid a is a biomarker of acute exacerbations of chronic obstructive pulmonary disease

S Bozinovski, A Hutchinson, M Thompson… - American journal of …, 2008 - atsjournals.org
Rationale: Much of the total disease burden and cost of chronic obstructive pulmonary
disease (COPD) is associated with acute exacerbations of COPD (AECOPD). Serum …

Serum amyloid A: an acute-phase protein involved in tumour pathogenesis

E Malle, S Sodin-Semrl, A Kovacevic - Cellular and molecular life sciences, 2009 - Springer
The synthesis of acute-phase protein serum amyloid A (SAA) is largely regulated by
inflammation-associated cytokines and a high concentration of circulating SAA may …

Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer

RM Ostroff, WL Bigbee, W Franklin, L Gold, M Mehan… - PloS one, 2010 - journals.plos.org
Background Lung cancer is the leading cause of cancer deaths worldwide. New diagnostics
are needed to detect early stage lung cancer because it may be cured with surgery …

Preferential localization of MUC1 glycoprotein in exosomes secreted by non-small cell lung carcinoma cells

D Pan, J Chen, C Feng, W Wu, Y Wang, J Tong… - International journal of …, 2019 - mdpi.com
Lung cancer remains to be the leading cause of cancer-related mortality worldwide. Finding
new noninvasive biomarkers for lung cancer is still a significant clinical challenge …

Applications of antibody array platforms

BB Haab - Current opinion in biotechnology, 2006 - Elsevier
Antibody arrays are valuable for the parallel analysis of multiple proteins in small sample
volumes. The earliest and most widely used application of antibody arrays has been to …