Microfluidic‐based approaches in targeted cell/particle separation based on physical properties: fundamentals and applications

R Nasiri, A Shamloo, S Ahadian, L Amirifar, J Akbari… - Small, 2020 - Wiley Online Library
Cell separation is a key step in many biomedical research areas including biotechnology,
cancer research, regenerative medicine, and drug discovery. While conventional cell sorting …

Recent advances in microfluidic cell sorting systems

Y Shen, Y Yalikun, Y Tanaka - Sensors and Actuators B: Chemical, 2019 - Elsevier
Effective and high-throughput cell sorting are critical technologies in single cell analysis in
biology, medicine and clinical applications. Especially for single cell analysis requiring high …

Microfluidics for label-free sorting of rare circulating tumor cells

S Zhu, F Jiang, Y Han, N Xiang, Z Ni - Analyst, 2020 - pubs.rsc.org
Circulating tumor cells (CTCs) have been widely considered as promising novel biomarkers
for molecular research and clinical diagnosis of cancer. However, the sorting of CTCs is very …

Active microfluidic systems for cell sorting and separation

M Sivaramakrishnan, R Kothandan… - Current Opinion in …, 2020 - Elsevier
Rapid progress in the field of microfluidics coupled with increase in demand for cell
separation techniques for biomedical diagnostics has gained significant attention among …

Design of a novel integrated microfluidic chip for continuous separation of circulating tumor cells from peripheral blood cells

MS Bakhshi, M Rizwan, GJ Khan, H Duan, K Zhai - Scientific Reports, 2022 - nature.com
Cancer is one of the foremost causes of death globally. Late-stage presentation,
inaccessible diagnosis, and treatment are common challenges in developed countries …

Recent advances in microfluidic technology for manipulation and analysis of biological cells (2007–2017)

MK Alam, E Koomson, H Zou, C Yi, CW Li, T Xu… - Analytica chimica …, 2018 - Elsevier
The pivotal role of microfluidic technology in life science and biomedical research is now
widely recognized. Indeed, microfluidics as a research tool is unparalleled in terms of its …

Impedance detection integrated with dielectrophoresis enrichment platform for lung circulating tumor cells in a microfluidic channel

NV Nguyen, CP Jen - Biosensors and Bioelectronics, 2018 - Elsevier
Enrichment and detection of rare cells are essential in many biological and medical
applications. In this study, circulating tumor cells were detected by combining …

Transcriptomics in toxicogenomics, part I: experimental design, technologies, publicly available data, and regulatory aspects

PAS Kinaret, A Serra, A Federico, P Kohonen… - Nanomaterials, 2020 - mdpi.com
The starting point of successful hazard assessment is the generation of unbiased and
trustworthy data. Conventional toxicity testing deals with extensive observations of …

Optically-induced-dielectrophoresis (ODEP)-based cell manipulation in a microfluidic system for high-purity isolation of integral circulating tumor cell (CTC) clusters …

TK Chiu, AC Chao, WP Chou, CJ Liao… - Sensors and Actuators B …, 2018 - Elsevier
Circulating tumor cell (CTC) clusters play a more critical role in cancer metastasis than
single CTCs. The study of CTC clusters might therefore provide more biologically …

Recent advances in continuous-flow particle manipulations using magnetic fluids

X Xuan - Micromachines, 2019 - mdpi.com
Magnetic field-induced particle manipulation is simple and economic as compared to other
techniques (eg, electric, acoustic, and optical) for lab-on-a-chip applications. However …