Most sensory, cognitive and motor functions depend on the interactions of many neurons. In
recent years, there has been rapid development and increasing use of technologies for …

Recent developments in the quantitative analysis of complex networks, based largely on
graph theory, have been rapidly translated to studies of brain network organization. The …

Neurons in cortical circuits are often coactivated as ensembles, yet it is unclear whether
ensembles play a functional role in behavior. Some ensemble neurons have pattern …

In many experiments, neuroscientists tightly control behavior, record many trials, and obtain
trial-averaged firing rates from hundreds of neurons in circuits containing billions of …

Neuronal ensembles are coactive groups of neurons that may represent building blocks of
cortical circuits. These ensembles could be formed by Hebbian plasticity, whereby synapses …

Technological advances have dramatically expanded our ability to probe multi-neuronal
dynamics and connectivity in the brain. However, our ability to extract a simple conceptual …

We consider the problem of extracting smooth low-dimensional neural trajectories''that
summarize the activity recorded simultaneously from tens to hundreds of neurons on …

Recent theoretical models suggest that deciding about actions and executing them are not
implemented by completely distinct neural mechanisms but are instead two modes of an …

Neuronal ensembles, coactive groups of neurons found in spontaneous and evoked cortical
activity, are causally related to memories and perception, but it is still unknown how stable or …

A systematic assessment of global neural network connectivity through direct
electrophysiological assays has remained technically infeasible, even in simpler systems …