Context Current literature suggests that several pathophysiological factors and mechanisms
might be responsible for the nonspecific symptom complex of overactive bladder (OAB) …

This article summarizes anatomical, neurophysiological, pharmacological, and brain
imaging studies in humans and animals that have provided insights into the neural circuitry …

Lower urinary tract (LUT) dysfunction is a common sequela of neurological disease,
resulting in symptoms that have a pronounced effect on quality of life. The site and nature of …

Micturition, or urination, occurs involuntarily in infants and young children until the age of 3
to 5 years, after which it is regulated voluntarily. The neural circuitry that controls this process …

This review and meta-analysis aims at summarizing and integrating the human
neuroimaging studies that report periaqueductal gray (PAG) involvement; 250 original …

Spinal cord injury (SCI) results not only in motor and sensory deficits but also in autonomic
dysfunctions. The disruption of connections between higher brain centers and the spinal …

Functions of the lower urinary tract to store and periodically eliminate urine are regulated by
a complex neural control system in the brain, spinal cord, and peripheral autonomic ganglia …

The central and autonomic nervous systems can be defined by their anatomical, functional
and neurochemical characteristics, but neither functions in isolation. For example …

Aim To review brain imaging studies of bladder control in subjects with normal control and
urge incontinence; to define a simple model of supraspinal bladder control; and to propose a …

The Piezo channel family, including Piezo1 and Piezo2, includes essential
mechanosensitive transduction molecules in mammals. Functioning in the conversion of …