Research in the last decade has expressed considerable optimism about the clinical
potential of psychedelics for the treatment of mental disorders. This optimism is reflected in …

Therapeutic claims about many psychedelic drugs have not been evaluated in any studies
of even modest rigor. The science of psychedelic drugs is strengthening however, making it …

Suicidal ideations (SI), often called suicidal thoughts or ideas, is a broad term used to
describe a range of contemplations, wishes, and preoccupations with death and suicide …

Major depressive disorder (MDD) is a highly prevalent and disabling disorder. Despite the
many hypotheses proposed to understand the molecular pathophysiology of depression, it is …

Abstract Background At-home Ketamine-assisted therapy (KAT) with psychosocial support
and remote monitoring through telehealth platforms addresses access barriers, including the …

Background: More than 2% of the general population experience suicidal ideas each year
and a large number of them will attempt suicide. Evidence-based therapeutic options to …

The discovery of ketamine as a rapid-acting antidepressant led to a new era in the
development of neuropsychiatric therapeutics, one characterized by an antidepressant …

Objective Suicide is a major cause of death in adolescents with limited treatment options.
Ketamine and its enantiomers have shown rapid anti-suicidal effects in adults with major …

Objectives: Ketamine is a glutamate N-methyl-D-aspartate receptor antagonist that can be
used to treat major depressive disorder by single or repeated infusions. However, the …

Introduction Ketamine is a pharmaceutical drug possessing both analgesic and anaesthetic
properties. As an anaesthetic, it induces anaesthesia by producing analgesia with a state of …