Extracellular matrix in the tumor microenvironment and its impact on cancer therapy
E Henke, R Nandigama, S Ergün - Frontiers in molecular biosciences, 2020 - frontiersin.org
Solid tumors are complex organ-like structures that consist not only of tumor cells but also of
vasculature, extracellular matrix (ECM), stromal, and immune cells. Often, this tumor …
vasculature, extracellular matrix (ECM), stromal, and immune cells. Often, this tumor …
Three‑dimensional cell culture: A powerful tool in tumor research and drug discovery
D Lv, Z Hu, L Lu, H Lu, X Xu - Oncology letters, 2017 - spandidos-publications.com
In previous years, three‑dimensional (3D) cell culture technology has become a focus of
research in tumor cell biology, using a variety of methods and materials to mimic the in vivo …
research in tumor cell biology, using a variety of methods and materials to mimic the in vivo …
Could 3D models of cancer enhance drug screening?
Cancer is a multifaceted pathology, where cellular and acellular players interact to drive
cancer progression and, in the worst-case, metastasis. The current methods to investigate …
cancer progression and, in the worst-case, metastasis. The current methods to investigate …
4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer
Hyaluronan (HA) is a prominent component of the extracellular matrix at many sites of
chronic inflammation, including type 1 diabetes (T1D), multiple sclerosis, and numerous …
chronic inflammation, including type 1 diabetes (T1D), multiple sclerosis, and numerous …
Scaffold-based 3D cell culture models in cancer research
Abstract Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer
research, offering significant advantages over traditional two-dimensional (2D) cell culture …
research, offering significant advantages over traditional two-dimensional (2D) cell culture …
Silk: a promising biomaterial opening new vistas towards affordable healthcare solutions
Substantial progress in biomaterial research over the years has culminated in revolutionary
technological advancements in the healthcare domain. This has triggered the quest for …
technological advancements in the healthcare domain. This has triggered the quest for …
Nonmulberry silk proteins: multipurpose ingredient in bio-functional assembly
The emerging field of tissue engineering and regenerative medicines utilising artificial
polymers is facing many problems. Despite having mechanical stability, non-toxicity and …
polymers is facing many problems. Despite having mechanical stability, non-toxicity and …
Silk as an innovative biomaterial for cancer therapy
K Jastrzebska, K Kucharczyk… - Reports of Practical …, 2015 - journals.viamedica.pl
Silk has been used for centuries in the textile industry and as surgical sutures. In addition to
its unique mechanical properties, silk possesses other properties, such as biocompatibility …
its unique mechanical properties, silk possesses other properties, such as biocompatibility …
Enhanced Metastatic Potential in a 3D Tissue Scaffold toward a Comprehensive in Vitro Model for Breast Cancer Metastasis
Metastasis is clinically the most challenging and lethal aspect of breast cancer. While animal-
based xenograft models are expensive and time-consuming, conventional two-dimensional …
based xenograft models are expensive and time-consuming, conventional two-dimensional …
[HTML][HTML] A novel platform for drug testing: Biomimetic three-dimensional hyaluronic acid-based scaffold seeded with human hepatocarcinoma cells
Hepatic cancer is one of the most widespread maladies worldwide that requires urgent
therapies and thus reliable means for testing anti-cancer drugs. The switch from two …
therapies and thus reliable means for testing anti-cancer drugs. The switch from two …