A cell is delimited by numerous borders that define specific organelles. The walls of some
organelles are particularly robust, such as in mitochondria or endoplasmic reticulum, but …

NGLY1/Ngly1 is a cytosolic peptide: N-glycanase, ie. de-N-glycosylating enzyme acting on
N-glycoproteins in mammals, generating free, unconjugated N-glycans and deglycosylated …

Lectins constitute an abundant group of proteins that are present throughout the plant
kingdom. Only recently, genome-wide screenings have unraveled the multitude of different …

Asparagine (N)-linked protein glycosylation, which takes place in the eukaryotic
endoplasmic reticulum (ER), is important for protein folding, quality control and the …

Abstract Peptide: N-glycanase (PNGase) is a de-N-glycosylating enzyme that cleaves intact
N-glycans from glycoproteins/glycopeptides. The activity of the cytoplasmic PNGase in …

Campylobacter jejuni is a major cause of bacterial gastroenteritis in humans that is primarily
associated with the consumption of inadequately prepared poultry products, since the …

Oligosaccharyltransferase (OST) is a key enzyme of the N-glycosylation pathway, where it
catalyzes the transfer of a glycan from a lipid-linked oligosaccharide (LLO) to an acceptor …

Oligosaccharyltransferases (OSTs) N-glycosylate proteins by transferring oligosaccharides
from lipid-linked oligosaccharides (LLOs) to asparaginyl residues of Asn-Xaa-Ser/Thr …

During asparagine (N)-linked protein glycosylation, eukaryotic cells generate considerable
amounts of free oligosaccharides (fOSs) in the cytosol. It is generally assumed that such …

Abstract Peptide: N-glycanase (PNGase) is a deglycosylating enzyme that acts on N-
glycoproteins. A growing evidence exists to indicate that the cytosolic form of PNGase, which …