Language disorders are highly heritable and are influenced by complex interactions
between genetic and environmental factors. Despite more than twenty years of research, we …

Severe speech disorders lead to poor literacy, reduced academic attainment and negative
psychosocial outcomes. As early as the 1950s, the familial nature of speech disorders was …

Genetic investigations of people with impaired development of spoken language provide
windows into key aspects of human biology. Over 15 years after FOXP2 was identified, most …

Objective Determining the genetic basis of speech disorders provides insight into the
neurobiology of human communication. Despite intensive investigation over the past 2 …

The goal of this research was to obtain initial estimates of the prevalence of each of four
types of motor speech disorders in children with idiopathic Speech Delay (SD) and to use …

Childhood apraxia of speech (CAS), the prototypic severe childhood speech disorder, is
characterized by motor programming and planning deficits. Genetic factors make …

Chromatin remodeling is of crucial importance during brain development. Pathogenic
alterations of several chromatin remodeling ATPases have been implicated in …

Background: Differential diagnosis and treatment planning of developmental speech
disorders (DSD) remains a major challenge in paediatric speech-language pathology …

FOXP transcription factors are an evolutionarily ancient protein subfamily coordinating the
development of several organ systems in the vertebrate body. Association of their genes …

Estimates of the prevalence of speech and motor speech disorders in persons with complex
neurodevelopmental disorders (CND) can inform research in the biobehavioural origins and …