State-dependent evolutionary models reveal modes of solid tumour growth
Spatial properties of tumour growth have profound implications for cancer progression,
therapeutic resistance and metastasis. Yet, how spatial position governs tumour cell division …
therapeutic resistance and metastasis. Yet, how spatial position governs tumour cell division …
Cell type evolution reconstruction across species through cell phylogenies of single-cell RNA sequencing data
The origin and evolution of cell types has emerged as a key topic in evolutionary biology.
Driven by rapidly accumulating single-cell datasets, recent attempts to infer cell type …
Driven by rapidly accumulating single-cell datasets, recent attempts to infer cell type …
Reconstructing cell type evolution across species through cell phylogenies of single-cell RNAseq data
The origin and evolution of cell types has emerged as a key topic in evolutionary biology.
Driven by rapidly accumulating single-cell datasets, recent attempts to infer cell type …
Driven by rapidly accumulating single-cell datasets, recent attempts to infer cell type …
Genomic and Transcriptomic Variant Detection through Long-read Single-cell RNA Sequencing in Ovarian Cancer
A Dondi - 2024 - research-collection.ethz.ch
During cancer development, clonal subpopulations with distinct genotypes and phenotypes
appear within a tumor, and some subpopulations might develop resistance to cancer …
appear within a tumor, and some subpopulations might develop resistance to cancer …
Phylogenetic inference from single-cell RNA-seq data
Tumors are comprised of subpopulations of cancer cells that harbor distinct genetic profiles
and phenotypes that evolve over time and during treatment. By reconstructing the course of …
and phenotypes that evolve over time and during treatment. By reconstructing the course of …