The nasal cavity is an attractive route for both local and systemic drug delivery and holds
great potential for access to the brain via the olfactory region, an area where the blood–brain …

Central nervous system (CNS) diseases are among the major health problems. However,
blood-brain barrier (BBB) makes traditional oral and intravenous delivery of CNS drugs …

The brain insulin metabolism alteration has been addressed as a pathophysiological factor
underlying Alzheimer's disease (AD). Insulin can be beneficial in AD, but its macro …

Efforts in discovering new and effective neurotherapeutics are made daily, although most fail
to reach clinical trials. The main reason is their poor bioavailability, related to poor aqueous …

A recommended first-line acute bacterial rhinosinusitis (ABR) treatment regimen includes a
high dose of orally administered amoxicillin, despite its frequent systemic adverse reactions …

Intranasally administered non-steroidal anti-inflammatory drugs (NSAIDs) offer an innovative
opportunity in the field of pain management. Combination of the nasal physiological …

The application of serum albumin in various types of formulations has emerged as a
valuable option in biomedical research, especially in the field of nasal drug delivery …

Our present series of experiments was to create a value-added formulation that has the
potential to exert a powerful and long-lasting antibacterial effect for use in ophthalmology …

Proper antibiotic use becomes a fundamental consideration to minimize the chance of
resistance threat. The nasal route has the potential as an appropriate way of administration …

Poor bioavailability of eye drops is a well-known issue, which can be improved by
increasing the residence time on the eye surface and the penetration of the active …