Rational design of biomaterials to potentiate cancer thermal therapy
Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …
eradicate mass lesions that are now defined as cancer. With the development of …
Recent applications of immunomodulatory biomaterials for disease immunotherapy
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
Enantiomer-dependent immunological response to chiral nanoparticles
Chirality is a unifying structural metric of biological and abiological forms of matter. Over the
past decade, considerable clarity has been achieved in understanding the chemistry and …
past decade, considerable clarity has been achieved in understanding the chemistry and …
Cancer nanomedicine for combination cancer immunotherapy
Cancer immunotherapy is revolutionizing oncology. However, dose-limiting toxicities and
low patient response rates remain major challenges in the clinic. Cancer nanomedicine in …
low patient response rates remain major challenges in the clinic. Cancer nanomedicine in …
Materials engineering strategies for cancer vaccine adjuvant development
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …
Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
Living macrophage-delivered tetrapod PdH nanoenzyme for targeted atherosclerosis management by ROS scavenging, hydrogen anti-inflammation, and autophagy …
Atherosclerosis, driven by chronic inflammation in the artery walls, underlies several severe
cardiovascular diseases. However, currently available anti-inflammatory-based strategies …
cardiovascular diseases. However, currently available anti-inflammatory-based strategies …
Nanoparticle toxicology
Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …
Modulation of immune responses by particle size and shape
The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …