Rational design of biomaterials to potentiate cancer thermal therapy

Y Zhu, Q Li, C Wang, Y Hao, N Yang, M Chen… - Chemical …, 2023 - ACS Publications
Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …

Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Enantiomer-dependent immunological response to chiral nanoparticles

L Xu, X Wang, W Wang, M Sun, WJ Choi, JY Kim… - Nature, 2022 - nature.com
Chirality is a unifying structural metric of biological and abiological forms of matter. Over the
past decade, considerable clarity has been achieved in understanding the chemistry and …

Cancer nanomedicine for combination cancer immunotherapy

J Nam, S Son, KS Park, W Zou, LD Shea… - Nature Reviews …, 2019 - nature.com
Cancer immunotherapy is revolutionizing oncology. However, dose-limiting toxicities and
low patient response rates remain major challenges in the clinic. Cancer nanomedicine in …

Materials engineering strategies for cancer vaccine adjuvant development

X Zhang, B Yang, Q Ni, X Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Living macrophage-delivered tetrapod PdH nanoenzyme for targeted atherosclerosis management by ROS scavenging, hydrogen anti-inflammation, and autophagy …

R Hu, C Dai, C Dong, L Ding, H Huang, Y Chen… - ACS …, 2022 - ACS Publications
Atherosclerosis, driven by chronic inflammation in the artery walls, underlies several severe
cardiovascular diseases. However, currently available anti-inflammatory-based strategies …

Nanoparticle toxicology

W Yang, L Wang, EM Mettenbrink… - Annual Review of …, 2021 - annualreviews.org
Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …

Modulation of immune responses by particle size and shape

MV Baranov, M Kumar, S Sacanna… - Frontiers in …, 2021 - frontiersin.org
The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …