This monograph, written by the pioneers of IVF and reproductive medicine, celebrates the
history, achievements, and medical advancements made over the last 40 years in this …

Culturing of human embryos in optimal conditions is crucial for a successful in vitro
fertilisation (IVF) programme. In addition, the capacity to assess and rank embryos correctly …

SUMMARY ANSWER: The present ESHRE document provides 11 recommendations on
how to introduce TLT in the IVF laboratory. WHAT IS KNOWN ALREADY: Studies have been …

The oviduct (known as the fallopian tube in humans) is the site for fertilization and pre-
implantation embryo development. Female steroid hormones, estrogen and progesterone …

The developmental competence of in vitro cultured (IVC) embryos is markedly lower than
that of their in vivo counterparts, suggesting the need for optimization of IVC protocols …

Developmental arrest of the preimplantation embryo is a multifactorial condition,
characterized by lack of cellular division for at least 24 hours, hindering the in vitro …

Background The high incidence of aneuploidy in early human development, arising either
from errors in meiosis or postzygotic mitosis, is the primary cause of pregnancy loss …

STUDY QUESTION Is blastocyst transfer safe when compared to cleavage stage embryo
transfer regarding obstetric and perinatal outcomes? SUMMARY ANSWER The clinical …

Over the past 4 decades our ability to maintain a viable human embryo in vitro has improved
dramatically, leading to higher implantation rates. This has led to a notable shift to single …

This proceedings report presents the outcomes from an international expert meeting to
establish consensus guidelines on IVF culture conditions. Topics reviewed and discussed …