Epigenetic mechanisms, which include DNA methylation, histone modification, and
microRNA (miRNA), can produce heritable phenotypic changes without a change in DNA …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by
progressive lung scarring and the histological picture of usual interstitial pneumonia (UIP). It …

Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous, unpredictable and ultimately
lethal chronic lung disease. Over the last decade, two anti-fibrotic agents have been shown …

MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

Idiopathic pulmonary fibrosis (IPF) is a fatal age-associated disease that is characterized by
progressive and irreversible scarring of the lung. The pathogenesis of IPF is not completely …

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and devastating interstitial
lung disease of unknown etiology, where the normal lung architecture is lost and replaced …

Fibrosis is a pathological feature of most chronic inflammatory diseases. Fibrosis, or
scarring, is defined by the accumulation of excess extracellular matrix components. If highly …

The discovery of the myofibroblast has opened new perspectives for the comprehension of
the biological mechanisms involved in wound healing and fibrotic diseases. In recent years …

Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease associated with
aging that is characterized by the histopathological pattern of usual interstitial pneumonia …

Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …