The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

Conspectus Fluorescent environment-sensitive probes are specially designed dyes that
change their fluorescence intensity (fluorogenic dyes) or color (eg, solvatochromic dyes) in …

Biomembranes constitute a basis for all compartments of live cells, and therefore, the
monitoring of their lipid organization is essential for understanding cell status and activity …

Single-molecule super-resolution microscopy has developed from a specialized technique
into one of the most versatile and powerful imaging methods of the nanoscale over the past …

The past decade has witnessed an explosion in the use of super-resolution fluorescence
microscopy methods in biology and other fields. Single-molecule localization microscopy …

Oligomers which form during amyloid fibril assembly are considered to be key contributors
towards amyloid disease. However, understanding how such intermediates form, their …

Protein aggregation is a complex process resulting in the formation of heterogeneous
mixtures of aggregate populations that are closely linked to neurodegenerative conditions …

Understanding the relations between the formation, structure, dynamics and functionality of
complex synthetic materials is one of the great challenges in chemistry and nanotechnology …

Visualization of the nanoscale organization of cell membranes remains challenging
because of the lack of appropriate fluorescent probes. Herein, we introduce a new design …

Protein misfolding and aggregation are characteristic of a wide range of neurodegenerative
disorders, including Alzheimer and Parkinson diseases. A hallmark of these diseases is the …