Flavonoid production: current trends in plant metabolic engineering and de novo microbial production
Flavonoids are secondary metabolites that represent a heterogeneous family of plant
polyphenolic compounds. Recent research has determined that the health benefits of fruits …
polyphenolic compounds. Recent research has determined that the health benefits of fruits …
The “beauty in the beast”—the multiple uses of Priestia megaterium in biotechnology
Over 30 years, the Gram-positive bacterium Priestia megaterium (previously known as
Bacillus megaterium) was systematically developed for biotechnological applications …
Bacillus megaterium) was systematically developed for biotechnological applications …
Hemoprotein catalyzed oxygenations: P450s, UPOs, and progress toward scalable reactions
G Grogan - JACS Au, 2021 - ACS Publications
The selective oxygenation of nonactivated carbon atoms is an ongoing synthetic challenge,
and biocatalysts, particularly hemoprotein oxygenases, continue to be investigated for their …
and biocatalysts, particularly hemoprotein oxygenases, continue to be investigated for their …
Production of plant natural products through engineered Yarrowia lipolytica
A Muhammad, X Feng, A Rasool, W Sun, C Li - Biotechnology Advances, 2020 - Elsevier
Plant natural products have broad applications in the pharmaceutical, food, cosmetics and
flavor industries. However, the current manufacturing methods for plant natural products …
flavor industries. However, the current manufacturing methods for plant natural products …
Efficient Biosynthesis of (2S)-Naringenin from p-Coumaric Acid in Saccharomyces cerevisiae
S Gao, Y Lyu, W Zeng, G Du, J Zhou… - Journal of agricultural …, 2019 - ACS Publications
(2 S)-Naringenin, a (2 S)-flavanone, is widely used in the food, chemical, and
pharmaceutical industries because of its diverse physiological activities. The production of …
pharmaceutical industries because of its diverse physiological activities. The production of …
Therapeutic potential of hesperidin and its aglycone hesperetin: Cell cycle regulation and apoptosis induction in cancer models
JMPF de Oliveira, C Santos, E Fernandes - Phytomedicine, 2020 - Elsevier
Background The ability of cancer cells to divide without restriction and to escape
programmed cell death is a feature of the proliferative state. Citrus flavanones are flavonoids …
programmed cell death is a feature of the proliferative state. Citrus flavanones are flavonoids …
Biological valorization of lignin to flavonoids
Lignin is the most affluent natural aromatic biopolymer on the earth, which is the promising
renewable source for valuable products to promote the sustainability of biorefinery …
renewable source for valuable products to promote the sustainability of biorefinery …
Whole-cell biocatalysis using cytochrome P450 monooxygenases for biotransformation of sustainable bioresources (fatty acids, fatty alkanes, and aromatic amino …
HA Park, G Park, W Jeon, JO Ahn, YH Yang… - Biotechnology …, 2020 - Elsevier
Cytochrome P450s (CYPs) are heme-thiolated enzymes that catalyze the oxidation of C
single bond H bonds in a regio and stereoselective manner. Activation of the non-activated …
single bond H bonds in a regio and stereoselective manner. Activation of the non-activated …
Systematically Engineered Fatty Acid Catabolite Pathway for the Production of (2S)-Naringenin in Saccharomyces cerevisiae
The (2 S)-naringenin is an important natural flavonoid with several bioactive effects on
human health. It is also a key precursor in the biosynthesis of other high value compounds …
human health. It is also a key precursor in the biosynthesis of other high value compounds …
A rapid and versatile tool for genomic engineering in Lactococcus lactis
T Guo, Y Xin, Y Zhang, X Gu, J Kong - Microbial Cell Factories, 2019 - Springer
Background Lactococcus lactis is one of the most extensively characterized lactic acid
bacteria, from physiological traits to industrial exploitation. Since last decade, L. lactis has …
bacteria, from physiological traits to industrial exploitation. Since last decade, L. lactis has …