Linking the Amyloid, Tau, and Mitochondrial Hypotheses of Alzheimer's Disease and Identifying Promising Drug Targets
Z Fišar - Biomolecules, 2022 - mdpi.com
Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …
[HTML][HTML] An updated review of randomized clinical trials testing the improvement of cognitive function of Ginkgo biloba extract in healthy people and Alzheimer's …
H Liu, M Ye, H Guo - Frontiers in Pharmacology, 2020 - frontiersin.org
Alzheimer's disease (AD) is a common neurodegenerative disease, mainly manifested by
cognitive dysfunction. It seriously reduces the quality of life, and there is no ideal treatment …
cognitive dysfunction. It seriously reduces the quality of life, and there is no ideal treatment …
AlCl3 induced learning and memory deficit in zebrafish
Aluminium is a metal known to cause neurotoxicity in the brain, by promoting
neurodegeneration and affecting memory and cognitive ability. AlCl 3 has been reported to …
neurodegeneration and affecting memory and cognitive ability. AlCl 3 has been reported to …
Tetrahydrobioterin (BH4) pathway: from metabolism to neuropsychiatry
H Fanet, L Capuron, N Castanon… - Current …, 2021 - ingentaconnect.com
Tetrahydrobipterin (BH4) is a pivotal enzymatic cofactor required for the synthesis of
serotonin, dopamine and nitric oxide. BH4 is essential for numerous physiological …
serotonin, dopamine and nitric oxide. BH4 is essential for numerous physiological …
Primary hypothyroidism and Alzheimer's Disease: a tale of two
FH AlAnazi, HM Al-Kuraishy, A Alexiou… - Cellular and Molecular …, 2023 - Springer
Hypothyroidism (HPT) HPT could be a risk factor for the development and progression of
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …
[HTML][HTML] Spatial memory and gut microbiota alterations are already present in early adulthood in a pre-clinical transgenic model of Alzheimer's disease
PC Bello-Medina, F Hernández-Quiroz… - Frontiers in …, 2021 - frontiersin.org
The irreversible and progressive neurodegenerative Alzheimer's disease (AD) is
characterized by cognitive decline, extracellular β-amyloid peptide accumulation, and tau …
characterized by cognitive decline, extracellular β-amyloid peptide accumulation, and tau …
Chronic-antibiotics induced gut microbiota dysbiosis rescues memory impairment and reduces β-amyloid aggregation in a preclinical Alzheimer's disease model
PC Bello-Medina, K Corona-Cervantes… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a multifactorial pathology characterized by β-amyloid (Aβ)
deposits, Tau hyperphosphorylation, neuroinflammatory response, and cognitive deficit …
deposits, Tau hyperphosphorylation, neuroinflammatory response, and cognitive deficit …
[HTML][HTML] Microglia-Mediated Inflammation and Neural Stem Cell Differentiation in Alzheimer's Disease: Possible Therapeutic Role of KV1.3 Channel Blockade
M Revuelta, J Urrutia, A Villarroel… - Frontiers in Cellular …, 2022 - frontiersin.org
Increase of deposits of amyloid β peptides in the extracellular matrix is landmark during
Alzheimer's Disease (AD) due to the imbalance in the production vs. clearance. This …
Alzheimer's Disease (AD) due to the imbalance in the production vs. clearance. This …
MicroRNA‑4722‑5p and microRNA‑615‑3p serve as potential biomarkers for Alzheimer's disease
Y Liu, Y Xu, M Yu - Experimental and therapeutic …, 2022 - spandidos-publications.com
The aim of the present study was to investigate the expression levels of microRNA (miR)‑
4722‑5p and miR‑615‑3p in Alzheimer's disease (AD) and their diagnostic value. Blood …
4722‑5p and miR‑615‑3p in Alzheimer's disease (AD) and their diagnostic value. Blood …
[HTML][HTML] The Wistar Kyoto rat: a model of depression traits
EE Redei, ME Udell, LCS Woods… - Current …, 2023 - ncbi.nlm.nih.gov
There is an ongoing debate about the value of animal research in psychiatry with valid lines
of reasoning stating the limits of individual animal models compared to human psychiatric …
of reasoning stating the limits of individual animal models compared to human psychiatric …