[HTML][HTML] Crosstalk between oxidative stress and inflammatory liver injury in the pathogenesis of alcoholic liver disease

YM Yang, YE Cho, S Hwang - International journal of molecular sciences, 2022 - mdpi.com
Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …

Inflammatory pathways in alcoholic steatohepatitis

B Gao, MF Ahmad, LE Nagy, H Tsukamoto - Journal of hepatology, 2019 - Elsevier
Inflammatory processes are primary contributors to the development and progression of
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …

[HTML][HTML] Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies

C Yao, S Dai, C Wang, K Fu, R Wu, X Zhao… - Biomedicine & …, 2023 - Elsevier
Luteolin is a flavonoid widely present in various traditional Chinese medicines. In recent
years, luteolin has received more attention due to its impressive liver protective effect, such …

Alcoholic liver disease

HK Seitz, R Bataller, H Cortez-Pinto, B Gao… - Nature reviews Disease …, 2018 - nature.com
Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …

Human ESC-derived expandable hepatic organoids enable therapeutic liver repopulation and pathophysiological modeling of alcoholic liver injury

S Wang, X Wang, Z Tan, Y Su, J Liu, M Chang, F Yan… - Cell research, 2019 - nature.com
We report the generation of human ESC-derived, expandable hepatic organoids (hEHOs)
using our newly established method with wholly defined (serum-free, feeder free) media …

Regulation and functional roles of chemokines in liver diseases

S Cao, M Liu, TS Sehrawat, VH Shah - Nature reviews Gastroenterology …, 2021 - nature.com
Inflammation is a major contributor to the pathogenesis of almost all liver diseases. Low-
molecular-weight proteins called chemokines are the main drivers of liver infiltration by …

Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB …

Z Ma, Y Lu, F Yang, S Li, X He, Y Gao, G Zhang… - Toxicology and Applied …, 2020 - Elsevier
Spinal cord injury (SCI) is a severe central nervous system injury for which few efficacious
drugs are available. Rosmarinic acid (RA), a water-soluble polyphenolic phytochemical, has …

[HTML][HTML] CBD alleviates liver injuries in alcoholics with high-fat high-cholesterol diet through regulating NLRP3 inflammasome–pyroptosis pathway

X Jiang, Y Gu, Y Huang, Y Zhou, N Pang… - Frontiers in …, 2021 - frontiersin.org
Alcohol abuse and high-fat diet–induced liver diseases have been the most prevalent
chronic liver diseases and the leading reasons for liver transplantation around the world …

[HTML][HTML] Effects of tea against alcoholic fatty liver disease by modulating gut microbiota in chronic alcohol-exposed mice

B Li, Q Mao, D Zhou, M Luo, R Gan, H Li, S Huang… - Foods, 2021 - mdpi.com
Gut microbiota dysbiosis has been a crucial contributor to the pathogenesis of alcoholic fatty
liver disease (AFLD). Tea is a popular beverage worldwide and exerts antioxidant and anti …

[HTML][HTML] Effect of vitexin on alleviating liver inflammation in a dextran sulfate sodium (DSS)-induced colitis model

S Duan, X Du, S Chen, J Liang, S Huang, S Hou… - Biomedicine & …, 2020 - Elsevier
As one of commonly used herbs with dual-purpose of drug and food, it has been reported
that vitexin has hepatoprotective effects. However, the protective effects of vitexin on colitis …